Methyltransferase-like factor 14 pathway and its relationship with pathological stages in patients undergoing surgery for colorectal cancer

Table 3 Comparison of methyltransferase-like factor 14 mRNA expression among patients with different clinicopathologies (mean ± SD)

Clinical pathology data	METTL14 mRNA expression	t	P value
Sex		1.724	0.089
Male (n = 43)	0.13 ± 0.03
Female (n = 37)	0.14 ± 0.02
Age (years)		1.205	0.232
≤ 60 (n = 48)	0.12 ± 0.04
> 60 (n = 32)	0.13 ± 0.03
Tissue typing		1.294	0.280
Poorly differentiated (n = 30)	0.13 ± 0.03
Moderately differentiated (n = 28)	0.12 ± 0.02
Well differentiated (n = 22)	0.12 ± 0.03
Tumor location		1.240	0.219
Rectal carcinoma (n = 52)	0.14 ± 0.04
Carcinoma of colon (n = 28)	0.13 ± 0.02
Tumor diameter (cm)		1.866	0.066
≤ 4 (n = 34)	0.13 ± 0.01
> 4 (n = 46)	0.14 ± 0.03
Lymphatic metastasis		5.878	< 0.001
Yes (n = 23)	0.10 ± 0.02
No (n = 57)	0.14 ± 0.03
Infiltration depth		8.780	< 0.001
T1 + T2 (n = 42)	0.16 ± 0.04
T3 + T4 (n = 38)	0.09 ± 0.03
TNM stage		43.442	< 0.001
I (n = 21)	0.16 ± 0.04
II (n = 30)	0.11 ± 0.03
III (n = 29)	0.08 ± 0.02

TNM: Tumor, node, and metastasis; METTL14: Methyltransferase-like factor 14.