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©The Author(s) 2025.
World J Gastrointest Surg. May 27, 2025; 17(5): 101674
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.101674
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.101674
Table 2 Comparison of methyltransferase-like factor 14 expression among patients with different clinicopathologies, n (%)
Clinical pathology data | Positive expression (n = 31) | Negative expression (n = 49) | χ2 | P value |
Gender | 0.024 | 0.877 | ||
Male (n = 43) | 17 (39.53) | 26 (60.47) | ||
Female (n = 37) | 14 (37.84) | 23 (62.16) | ||
Age (years) | 0.079 | 0.779 | ||
≤ 60 (n = 48) | 18 (37.50) | 30 (62.50) | ||
> 60 (n = 32) | 13 (40.63) | 19 (59.37) | ||
Tissue typing | 0.427 | 0.808 | ||
Poorly differentiated (n = 30) | 13 (43.33) | 17 (56.67) | ||
Moderately differentiated (n = 28) | 10 (35.71) | 18 (64.29) | ||
Well differentiated (n = 22) | 8 (36.36) | 14 (63.67) | ||
Tumor location | 0.026 | 0.872 | ||
Rectal carcinoma (n = 52) | 20 (38.46) | 32 (60.54) | ||
Carcinoma of colon (n = 28) | 11 (39.29) | 17 (60.71) | ||
Tumor diameter (cm) | 0.007 | 0.935 | ||
≤ 4 (n = 34) | 13 (38.24) | 21 (61.76) | ||
> 4 (n = 46) | 18 (39.13) | 28 (60.87) | ||
Lymphatic metastasis | 8.988 | 0.003 | ||
Yes (n = 23) | 3 (13.04) | 20 (86.96) | ||
No (n = 57) | 28 (49.12) | 29 (50.88) | ||
Infiltration depth | 12.603 | 0.001 | ||
T1 + T2 (n = 42) | 24 (57.14) | 18 (42.86) | ||
T3 + T4 (n = 38) | 7 (18.42) | 31 (81.58) | ||
TNM stage | 15.393 | 0.001 | ||
I (n = 21) | 18 (85.71) | 3 (14.29) | ||
II (n = 30) | 10 (33.33) | 20 (66.67) | ||
III (n = 29) | 3 (10.34) | 26 (89.64) |
- Citation: Dai Q, Ma PF, Tian J, Zhang Z, Fang Q, Lin ZY, Wu LL, Li XM. Methyltransferase-like factor 14 pathway and its relationship with pathological stages in patients undergoing surgery for colorectal cancer. World J Gastrointest Surg 2025; 17(5): 101674
- URL: https://www.wjgnet.com/1948-9366/full/v17/i5/101674.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i5.101674