Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII

Table 6 Univariate and multivariate analysis of prognostic factors for recurrence-free survival in first recurrence data

Variable	Before PS matching (n = 36)				After PS matching (n = 32)
	Univariate		Multivariate		Univariate		Multivariate
	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
Treatment	0.32 (0.13-0.81)	0.016	0.29 (0.09-0.97)	0.043	0.39 (0.15-1.00)	0.051	0.46 (0.13-1.61)	0.226
Age	0.99 (0.95-1.03)	0.586			1.00 (0.96-1.05)	0.847
Gender	2.77 (0.97-7.95)	0.058	6.60 (1.79-24.32)	0.004	3.22 (1.12-9.28)	0.030	6.81 (1.98-23.41)	0.002
HBV	0.61 (0.25-1.47)	0.267			0.74 (0.30-1.82)	0.508
HCV	1.04 (0.40-2.72)	0.937			0.88 (0.33-2.33)	0.795
ICG-R15 < 10%	1.22 (0.48-3.07)	0.675			2.42 (0.88-6.66)	0.088	1.33 (0.37-4.84)	0.660
Platelet	0.99 (0.99-1.00)	0.137	0.99 (0.98-1.00)	0.129	1.00 (0.99-1.00)	0.321
Prothrombin time	1.35 (0.95-1.92)	0.098	1.21 (0.88-1.66)	0.235	1.29 (0.90-1.87)	0.167	1.28 (0.91-1.80)	0.153
AST	1.00 (1.00-1.00)	0.418			1.00 (1.00-1.00)	0.672
ALT	1.00 (1.00-1.00)	0.74			1.00 (1.00-1.00)	0.782
AFP ≥ 100 ng/mL	2.09 (0.82-5.32)	0.12	2.60 (0.72-9.44)	0.145	2.69 (1.04-6.97)	0.041	2.08 (0.54-8.01)	0.285
Bilirubin total	1.72 (0.63-4.70)	0.293			1.26 (0.43-3.70)	0.675
Albumin	0.69 (0.24-1.98)	0.491			0.63 (0.23-1.73)	0.369
ALBI	1.44 (0.52-3.97)	0.482			1.28 (0.42-3.88)	0.66
Child-Pugh	1.32 (0.38-4.53)	0.658			1.15 (0.33-3.98)	0.824
T stage	1.36 (0.60-3.08)	0.455			1.34 (0.59-3.04)	0.482
Major tumor size	1.01 (0.67-1.53)	0.951			1.08 (0.68-1.71)	0.743
Aggregate tumor size	1.08 (0.89-1.32)	0.436			1.12 (0.93-1.35)	0.214
Tumor numbers	1.30 (0.85-1.98)	0.224			1.30 (0.87-1.95)	0.202
BCLC	1.08 (0.50-2.31)	0.843			1.41 (0.64-3.14)	0.397
SAS	0.74 (0.29-1.85)	0.514			1.02 (0.40-2.60)	0.967
Complication	4.20 (1.65-10.70)	0.003	3.62 (1.09-11.96)	0.034	3.78 (1.46-9.75)	0.006	3.08 (0.76-12.44)	0.114

HBV: Hepatitis B virus; HCV: Hepatitis C virus; ICG-R15: Indocyanine green retention rate at 15 minutes; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AFP: Alpha-fetoprotein; ALBI: Albumin-Bilirubin grade; BCLC: Barcelona Clinic Liver Cancer; SAS: Surgical Apgar Score; PS: Propensity score; HR: Hazard ratio; CI: Confidence interval.