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Retrospective Study
©The Author(s) 2025.
World J Gastrointest Surg. Dec 27, 2025; 17(12): 113940
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113940
Table 4 Univariate and multivariate analysis of prognostic factors for recurrence-free survival in de novo data
Variable
Before PS matching (n = 36)
After PS matching (n = 32)
Univariate
Multivariate
Univariate
Multivariate
HR (95%CI)
P value
HR (95%CI)
P value
HR (95%CI)
P value
HR (95%CI)
P value
Treatment0.13 (0.02-0.66)0.0141.15 (0.01-264.01)0.9600.16 (0.03-0.83)0.0290.92 (0.00-299.08)0.977
Age1.00 (0.95-1.07)0.8861.01 (0.95-1.08)0.782
Gender0.54 (0.07-4.30)0.5560.54 (0.07-4.38)0.565
HBV1.26 (0.31-5.08)0.7421.62 (0.40-6.51)0.498
HCV0.67 (0.14-3.22)0.6140.53 (0.11-2.59)0.436
ICG-R15 < 10%1.82 (0.49-6.80)0.3733.35 (0.88-12.70)0.076100.80 (0.28-36753.83)0.125
Platelet1.00 (0.99-1.01)0.5141.00 (0.99-1.01)0.872
Prothrombin time1.60 (1.11-2.30)0.01116.45 (0.51-528.83)0.1141.55 (1.09-2.20)0.0153.06 (0.10-93.96)0.522
AST1.00 (1.00-1.00)0.1271.00 (0.99-1.01)0.9701.00 (1.00-1.00)0.1801.00 (0.99-1.01)0.643
ALT1.00 (1.00-1.00)0.9551.00 (1.00-1.00)0.882
AFP ≥ 100 ng/mL2.36 (0.63-8.84)0.2032.41 (0.64-9.01)0.1911.65 (0.07-36.92)0.753
Bilirubin total1.15 (0.24-5.58)0.8610.97 (0.19-5.03)0.970
Albumin0.41 (0.12-1.38)0.15026.60 (0.34-2088.41)0.1410.41 (0.13-1.25)0.1157.23 (0.07-799.58)0.410
ALBI1.18 (0.25-5.71)0.8341.31 (0.27-6.34)0.738
Child-Pugh2.08 (0.43-10.07)0.3621.77 (0.37-8.54)0.479
T stage3.79 (1.16-12.31)0.0270.09 (0.00-4.55)0.2253.87 (1.22-12.25)0.0210.31 (0.01-18.91)0.577
Major tumor size1.35 (0.83-2.20)0.2281.51 (0.93-2.43)0.0953.89 (0.07-211.13)0.505
Aggregate tumor size1.30 (1.05-1.61)0.0161.57 (0.70-3.56)0.2761.32 (1.08-1.61)0.0071.33 (0.38-4.66)0.652
Tumor numbers1.70 (0.99-2.91)0.0554.65 (0.77-27.97)0.0931.62 (0.95-2.76)0.07612.29 (0.28-534.39)0.192
BCLC2.87 (0.88-9.38)0.08226.75 (0.89-803.48)0.0583.70 (1.10-12.41)0.0340.99 (0.00-395.47)0.997
SAS0.80 (0.20-3.20)0.7491.00 (0.25-4.01)0.998
Complication7.29 (1.94-27.33)0.003142.17 (0.37-55319.72)0.1036.14 (1.64-23.03)0.0070.42 (0.00-83.99)0.750


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