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Retrospective Study
©The Author(s) 2025.
World J Gastrointest Surg. Dec 27, 2025; 17(12): 113940
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113940
Table 3 Univariate and multivariate analysis of prognostic factors for overall survival in de novo data
Variable
Before PS matching (n = 57)
After PS matching (n = 16)
Univariate
Multivariate
Univariate
Multivariate
HR (95%CI)
P value
HR (95%CI)
P value
HR (95%CI)
P value
HR (95%CI)
P value
Treatment0.61 (0.18-2.14)0.4430.58 (0.10-3.47)0.548
Age1.03 (0.98-1.08)0.1931.04 (0.99-1.10)0.1501.15 (0.97-1.37)0.1071.63 (0.74-3.56)0.224
Gender2.55 (1.00-6.49)0.0504.98 (1.03-24.06)0.0460.57 (0.06-5.12)0.613
HBV0.83 (0.32-2.15)0.7060.81 (0.13-4.89)0.818
HCV0.70 (0.23-2.13)0.5280.36 (0.04-3.27)0.363
ICG-R15 < 10%0.62 (0.20-1.89)0.4030.00 (0.00-inf)0.995
Platelet1.00 (0.99-1.00)0.4581.00 (0.98-1.02)0.988
Prothrombin time1.09 (0.74-1.59)0.6742.80 (0.69-11.37)0.1516.42 (0.17-249.92)0.319
AST1.00 (1.00-1.00)0.9731.00 (1.00-1.00)0.772
ALT1.00 (1.00-1.00)0.8691.00 (1.00-1.00)0.594
AFP ≥ 100 ng/mL1.15 (0.33-3.99)0.8230.00 (0.00-inf)0.996
Bilirubin total0.48 (0.09-2.71)0.4090.30 (0.00-22.14)0.584
Albumin0.55 (0.20-1.53)0.2520.12 (0.01-1.48)0.09831.48 (0.00-3.6 × 109)0.716
ALBI1.56 (0.51-4.73)0.4356.28 (0.86-45.89)0.0730.75 (0.00-8.2 × 106)0.591
Child-Pugh0.00 (0.00-inf)0.9960.00 (0.00-inf)0.996
T stage1.23 (0.62-2.42)0.5540.54 (0.09-3.09)0.489
Major tumor size1.18 (0.97-1.44)0.1061.40 (0.53-3.70)0.4971.64 (0.58-4.62)0.346
Aggregate tumor size1.16 (0.96-1.42)0.1320.95 (0.38-2.37)0.9051.28 (0.46-3.62)0.638
Tumor numbers0.88 (0.34-2.32)0.8000.00 (0.00-inf)0.996
BCLC1.59 (0.72-3.49)0.2490.71 (0.15-3.42)0.67
SAS0.95 (0.38-2.41)0.9172.26 (0.38-13.60)0.373
Complication1.07 (0.31-3.72)0.9116.28 (0.86-45.89)0.070.05 (0.00-2.7 × 1012)0.853


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