Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII

doi:10.4240/wjgs.v17.i12.113940

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Dec 27, 2025; 17(12): 113940
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113940

Table 2 Comparison of the baseline characteristics between the robotic liver resection and robotic intraoperative radiofrequency ablation groups before and after matching in first recurrence data, n (%)/median (interquartile range)

Variable	Before PS matching			After PS matching
Variable	RIO-RFA (n = 8)	R-LR (n = 49)	P value	RIO-RFA (n = 8)	R-LR (n = 8)	P value
Age (years)	71.5 (62.8-75.0)	68.0 (63.0-75.5)	0.8608	71.5 (62.8-75.0)	67.0 (63.0-74.0)	0.7769
Male	14 (87.5)	16 (80.0)	0.6722	14 (87.5)	13 (81.2)	1
Height (cm)	164.0 (157.2-170.5)	166.5 (158.8-169.2)	0.8984	164.0 (157.2-170.5)	167.5 (163.2-169.2)	0.7196
Weight (kg)	64.5 (54.5-78.5)	65.5 (61.5-75.0)	0.7258	64.5 (54.5-78.5)	71.2 (63.8-75.2)	0.4063
BMI (kg/m²)	25.9 (20.7-27.0)	26.2 (23.1-26.9)	0.6906	25.9 (20.7-27.0)	26.3 (24.5-27.0)	0.534
HBV	8 (50.0)	14 (70.0)	0.3793	8 (50.0)	10 (62.5)	0.7216
HCV	4 (25.0)	6 (30.0)	1	4 (25.0)	6 (37.5)	0.7043
ICG-R15 < 10%	5 (31.2)	7 (35.0)	1	5 (31.2)	3 (18.8)	0.6851
Platelet (10³/mL)	116.5 (89.5-151.5)	123.0 (103.8-156.5)	0.4737	116.5 (89.5-151.5)	117.5 (98.0-145.0)	0.91
Prothrombin time (s)	10.9 (10.5-11.0)	10.5 (10.3-10.9)	0.0867	10.9 (10.5-11.0)	10.6 (10.4-10.9)	0.2882
AST (U/L)	323.0 (155.2-1067.2)	194.0 (126.0-323.0)	0.1345	323.0 (155.2-1067.2)	204.0 (126.8-323.0)	0.2
ALT (U/L)	266.5 (174.0-762.0)	274.5 (130.0-437.5)	0.4544	266.5 (174.0-762.0)	225.5 (130.0-384.2)	0.3558
AFP ≥ 100 ng/mL	4 (25.0)	5 (25.0)	1	4 (25.0)	4 (25.0)	1
Bilirubin total (mg/dL)	1.0 (0.6-1.4)	0.9 (0.7-1.1)	0.3973	1.0 (0.6-1.4)	0.9 (0.7-1.1)	0.5962
Albumin (g/dL)	4.5 (4.0-4.6)	4.3 (4.0-4.7)	0.7736	4.5 (4.0-4.6)	4.5 (4.1-4.7)	0.4602
ALBI (grade 1/2)	12 (75.0)/4 (25.0)	16 (80.0)/4 (20.0)	1	12 (75.0)/4 (25.0)	13 (81.2)/3 (18.8)	1
Child-Pugh (class A/B)	12 (75.0)/4 (25.0)	18 (90.0)/2 (10.0)	0.3738	12 (75.0)/4 (25.0)	14 (87.5)/2 (12.5)	0.6539
T stage (1/2/3/4)	5 (31.2)/10 (62.5)/1 (6.2)	13 (65.0)/6 (30.0)/1 (5.0)	0.1248	5 (31.2)/10 (62.5)/1 (6.2)	11 (68.8)/4 (25.0)/1 (6.2)	0.0898
Major tumor size (cm)	2.3 (1.7-2.7)	1.9 (1.5-2.8)	0.5133	2.3 (1.7-2.7)	1.9 (1.3-2.2)	0.2993
Aggregate tumor size (cm)	3.3 (2.4-5.3)	2.0 (1.8-3.4)	0.0581	3.3 (2.4-5.3)	1.9 (1.6-2.7)	0.0184
Tumor numbers (1/2/3/4/5)	7 (43.8)/4 (25.0)/3 (18.8)/1 (6.2)/1 (6.2)	13 (65.0)/5 (25.0)/2 (10.0)/0 (0)/0 (0)	0.4463	7 (43.8)/4 (25.0)/3 (18.8)/1 (6.2)/1 (6.2)	11 (68.8)/3 (18.8)/2 (12.5)/0 (0)/0 (0)	0.5198
Multi-tumors	9 (56.2)	7 (35.0)	0.3485	9 (56.2)	5 (31.2)	0.285
BCLC (stage 0/A/B)	1 (6.2)/12 (75.0)/3 (18.8)	6 (30.0)/12 (60.0)/2 (10.0)	0.1856	1 (6.2)/12 (75.0)/3 (18.8)	6 (37.5)/9 (56.2)/1 (6.2)	0.0821
Operation time (minutes)	109.5 (100.0-175.5)	167.5 (128.5-197.2)	0.1043	109.5 (100.0-175.5)	164.5 (128.5-176.0)	0.1998
SAS (score 2/3)	9 (56.2)/7 (43.8)	12 (60.0)/8 (40.0)	1	9 (56.2)/7 (43.8)	11 (68.8)/5 (31.2)	0.715
Blood loss (mL)	10.0 (10.0-55.0)	175.0 (77.5-326.2)	0.0046	10.0 (10.0-55.0)	175.0 (10.0-266.2)	0.0174
Blood transfusion	5 (31.2)	7 (35.0)	1	5 (31.2)	5 (31.2)	1
Complication	5 (31.2)	2 (10.0)	0.2036	5 (31.2)	2 (12.5)	0.3944
Hospital stays (days)	8.0 (7.0-11.0)	9.0 (7.8-12.0)	0.3857	8.0 (7.0-11.0)	9.0 (7.8-10.5)	0.5055

BMI: Body mass index; HBV: Hepatitis B virus; HCV: Hepatitis C virus; ICG-R15: Indocyanine green retention rate at 15 minutes; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AFP: Alpha-fetoprotein; ALBI: Albumin-Bilirubin grade; BCLC: Barcelona Clinic Liver Cancer; SAS: Surgical Apgar Score; PS: Propensity score; RIO-RFA: Robotic intraoperative RFA; R-LR: Robotic liver resection.

Full Size Table

Citation: Peng CM, Lin SC, Cheng YY, Cheng TC, Hsieh CL, Hsieh CH, Hsieh MF, Liao CH, Liu MC, Liu YJ. Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII. World J Gastrointest Surg 2025; 17(12): 113940
URL: https://www.wjgnet.com/1948-9366/full/v17/i12/113940.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i12.113940

Peng CM, Lin SC, Cheng YY, Cheng TC, Hsieh CL, Hsieh CH, Hsieh MF, Liao CH, Liu MC, Liu YJ. Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII. World J Gastrointest Surg 2025; 17(12): 113940 [PMID: 41479724 DOI: 10.4240/wjgs.v17.i12.113940]

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