Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII

doi:10.4240/wjgs.v17.i12.113940

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Dec 27, 2025; 17(12): 113940
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.113940

Table 1 Comparison of the baseline characteristics between the robotic liver resection and robotic intraoperative radiofrequency ablation groups before and after matching in de novo data, n (%)/median (interquartile range)

Variable	Before PS matching			After PS matching
Variable	RIO-RFA (n = 8)	R-LR (n = 49)	P value	RIO-RFA (n = 8)	R-LR (n = 8)	P value
Age (years)	71.5 (68.5-74.2)	68.0 (62.0-77.0)	0.621	71.5 (68.5-74.2)	68.0 (58.8-77.5)	0.713
Male	5 (62.5)	31 (63.3)	1	5 (62.5)	5 (62.5)	1
Height (cm)	164.5 (159.8-170.2)	162.0 (157.0-168.0)	0.4009	164.5 (159.8-170.2)	162.0 (156.5-166.5)	0.4613
Weight (kg)	66.5 (64.8-71.0)	66.0 (53.0-75.0)	0.5424	66.5 (64.8-71.0)	60.0 (52.8-69.8)	0.3998
BMI (kg/m²)	24.5 (23.0-25.4)	23.4 (20.8-26.9)	0.6116	24.5 (23.0-25.4)	23.0 (21.1-24.8)	0.3823
HBV	5 (62.5)	33 (67.3)	1	5 (62.5)	6 (75.0)	1
HCV	3 (37.5)	13 (26.5)	0.6735	3 (37.5)	2 (25.0)	1
ICG-R15 < 10%	1 (12.5)	16 (32.7)	0.4133	1 (12.5)	2 (25.0)	1
Platelet (10³/mL)	127.5 (97.2-156.5)	169.0 (135.0-215.0)	0.0179	127.5 (97.2-156.5)	135.5 (110.0-160.0)	0.713
Prothrombin time (s)	10.8 (10.7-11.1)	10.6 (10.3-11.1)	0.295	10.8 (10.7-11.1)	10.8 (10.4-11.0)	0.5621
AST (U/L)	106.5 (79.0-460.8)	244.0 (82.0-511.0)	0.5972	106.5 (79.0-460.8)	329.0 (174.0-857.5)	0.1304
ALT (U/L)	112.0 (75.2-444.5)	307.0 (120.0-532.0)	0.2802	112.0 (75.2-444.5)	366.5 (209.0-1018.8)	0.1605
AFP ≥ 100 ng/mL	2 (25.0)	8 (16.3)	0.6194	2 (25.0)	1 (12.5)	1
Bilirubin total (mg/dL)	0.9 (0.8-1.1)	0.8 (0.6-0.9)	0.2478	0.9 (0.8-1.1)	0.9 (0.8-1.0)	1
Albumin (g/dL)	4.2 (4.0-4.6)	4.4 (4.1-4.7)	0.5567	4.2 (4.0-4.6)	4.6 (4.4-4.7)	0.2448
ALBI (grade 1/2)	6 (75.0)/2 (25.0)	42 (85.7)/7 (14.3)	0.599	6 (75.0)/2 (25.0)	7 (87.5)/1 (12.5)	1
Child-Pugh (class A/B)	7 (87.5)/1 (12.5)	48 (98.0)/1 (2.0)	0.2632	7 (87.5)/1 (12.5)	8 (100.0)/0 (0.0)	1
T stage (1/2/3/4)	6 (75.0)/1 (12.5)/0 (0.0)/1 (12.5)	36 (73.5)/12 (24.5)/1 (2.0)/0 (0.0)	0.0812	6 (75.0)/1 (12.5)/1(12.5)	5 (62.5)/3 (37.5)/0 (0.0)	0.3515
Major tumor size (cm)	1.6 (1.5-2.3)	3.0 (1.8-4.5)	0.0343	1.6 (1.5-2.3)	2.1 (1.6-3.0)	0.4589
Aggregate tumor size (cm)	1.6 (1.6-2.8)	3.1 (2.1-4.5)	0.071	1.6 (1.6-2.8)	2.5 (1.9-3.0)	0.5249
Tumor numbers (1/2/3/4)	5 (62.5)/1 (12.5)/1 (12.5)/1 (12.5)	39 (79.6)/10 (30.4)/0 (0)/0 (0)	0.0053	5 (62.5)/1 (12.5)/1(12.5)/1 (12.5)	7 (87.5)/1 (12.5)/0 (0)/0 (0)	0.5062
Multi-tumors	3 (37.5)	10 (20.4)	0.3653	3 (37.5)	1 (12.5)	0.5692
BCLC (stage 0/A/B)	3 (37.5)/4 (50.0)/1 (12.5)	9 (18.4)/31 (63.3)/9 (18.4)	0.4658	3 (37.5)/4 (50.0)/1(12.5)	2 (25.0)/6 (75.0)/0 (0.0)	0.4493
Operation time (minutes)	104.0 (68.8-128.8)	175.0 (155.0-249.0)	0.0002	104.0 (68.8-128.8)	114.5 (93.0-182.8)	0.2698
SAS (score 2/3)	5 (62.5)/3 (37.5)	26 (53.1)/23 (46.9)	0.7153	5 (62.5)/3 (37.5)	4 (50.0)/4 (50.0)	1
Blood loss (mL)	10.0 (10.0-10.0)	350.0 (105.0-805.0)	0.0003	10.0 (10.0-10.0)	80.0 (10.0-117.5)	0.1179
Blood transfusion	2 (25.0)	31 (63.3)/18 (36.7)	0.6993	2 (25.0)	2 (25.0)	1
Complication	1 (12.5)	11 (22.4)	1	1 (12.5)	2 (25.0)	1
Hospital stays (days)	9.5 (9.0-10.0)	11.0 (9.0-14.0)	0.3604	9.5 (9.0-10.0)	10.5 (10.0-13.5)	0.1151

BMI: Body mass index; HBV: Hepatitis B virus; HCV: Hepatitis C virus; ICG-R15: Indocyanine green retention rate at 15 minutes; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AFP: Alpha-fetoprotein; ALBI: Albumin-Bilirubin grade; BCLC: Barcelona Clinic Liver Cancer; SAS: Surgical Apgar Score; PS: Propensity score; RIO-RFA: Robotic intraoperative RFA; R-LR: Robotic liver resection.

Full Size Table

Citation: Peng CM, Lin SC, Cheng YY, Cheng TC, Hsieh CL, Hsieh CH, Hsieh MF, Liao CH, Liu MC, Liu YJ. Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII. World J Gastrointest Surg 2025; 17(12): 113940
URL: https://www.wjgnet.com/1948-9366/full/v17/i12/113940.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i12.113940

Peng CM, Lin SC, Cheng YY, Cheng TC, Hsieh CL, Hsieh CH, Hsieh MF, Liao CH, Liu MC, Liu YJ. Outcomes of robotic liver resection and intraoperative radiofrequency ablation for hepatocellular carcinoma in posterior segments VII and VIII. World J Gastrointest Surg 2025; 17(12): 113940 [PMID: 41479724 DOI: 10.4240/wjgs.v17.i12.113940]

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