Nomogram for prediction of six-month mortality following endovascular treatment of delayed post-pancreatectomy hemorrhage

Table 4 Univariate and multivariate logistic regression analysis of mortality risk factors in patients with delayed post-pancreatectomy hemorrhage

Characteristics	Univariate analysis		Multivariate analysis
	P value	OR (95%CI)	P value	OR 95%CI
Gender	0.1787	1.143 (0.942-1.388)
Age	0.0327	0.990 (0.980-0.999)	0.0018	1.014 (1.005-1.022)
Hypertension	0.0758	1.185 (0.985-1.425)
Diabetes mellitus	0.0300	0.732 (0.555-0.966)
In-hospital days	0.0301	1.003 (1.000-1.006)	< 0.001	0.996 (0.993-0.998)
Pathology diagnosis	0.5150	0.925 (0.732-1.169)
Preoperative total bilirubin	0.6898	1 (0.999-1.001)
Preoperative direct bilirubin	0.4815	1 (0.999-1.002)
Operating duration	0.0760	1 (0.999-1)	0.0044	1.001 (1-1.001)
POPF	0.0350	0.8 (0.667-0.982)
Gastrointestinal fistula	0.7108	1.1 (0.72-1.622)
Bile leakage	0.445	0.9 (0.7-1.169)
Intra-abdominal infection	0.0412	0.8 (0.685-0.99)	0.0053	1.253 (1.074-1.462)
Bleeding latency, days	0.5931	1 (0.997-1.005)
Hemoglobin	0.6565	1 (0.995-1.007)
PLT	0.0799	1 (1-1.002)
APTT	0.0379	1 (0.988-1)	0.0159	0.991 (0.984-0.998)
INR	0.0001	0.7 (0.565-0.819)	0.0113	1.374 (1.081-1.746)
Coagulopathy	0.0051	0.8 (0.629-0.916)	0.0732	1.204 (0.985-1.471)
Severity of PPH-grade B or C	0.0642	0.8 (0.693-1.008)
Asymptomatic hemorrhage	0.0372	1.3 (1.019-1.64)
Pseudoaneurysm detected on postoperative follow-up CT	0.2858	1.3 (0.792-2.22)
Melena or/and hematemesis	1.0000	1 (0.823-1.215)
Sentinel bleeding	0.8936	1 (0.833-1.232)
Hemorrhagic shock	0.0200	0.8 (0.661-0.961)
Strategy of embolization	0.0615	0.8 (0.636-1.008)
Negative on angiography	0.0372	1.3 (1.019-1.64)
Suspicious of contrast agent staining	0.3868	1.3 (0.705-2.479)
Vessel stenosis	0.5229	0.9 (0.734-1.17)
Pseudoaneurysm	0.8538	1 (0.802-1.201)
Contrast medium overflow	0.0051	0.8 (0.629-0.916)
Stump of gastroduodenal artery sign	0.3308	1.2 (0.849-1.629)
Conservative treatment	0.1873	1.2 (0.923-1.516)
Common hepatic artery	0.0454	0.8 (0.687-0.993)	0.0256	1.182 (1.023-1.364)
SMA	0.0933	1.3 (0.955-1.894)
Proper hepatic artery	0.9368	1 (0.696-1.396)
Right hepatic artery	0.8131	0.9 (0.559-1.577)
Left hepatic artery	0.8131	0.9 (0.559-1.577)
Left gastric artery	0.4271	1.2 (0.814-1.629)
Coils	0.0628	0.8 (0.678-1.008)
Stent	0.3308	1.2 (0.849-1.629)
Gelatin sponges	0.9180	1 (0.652-1.609)
NBCA	0.4711	0.8 (0.422-1.488)
Number of post-Whipple interventional embolization	0.6321	1.1 (0.819-1.391)
Number of post-Whipple open abdominal surgeries	0.1404	0.9 (0.71-1.048)
Tech success	0.3402	1.2 (0.838-1.674)
Clinical success	0.0002	1.4 (1.193-1.7)	0.0167	0.813 (0.688-0.96)
Re-bleeding	0.7587	1 (0.771-1.208)

POPF: Postoperative pancreatic fistula; PLT: Platelet count; APTT: Activated partial thromboplastin time; INR: International normalized ratio; PPH: Post-pancreatectomy hemorrhage; CT: Computed tomography; SMA: Superior mesenteric artery; NBCA: N-butyl cyanoacrylate; OR: Odds ratio; CI: Confidence interval.