Intra-abdominal pressure and procalcitonin for prognosis in patients with severe acute pancreatitis: An etiology-based analysis

Table 1 Baseline characteristics of the study participants

Characteristics	Total (n = 245)	Training set (n = 172)	Validation set (n = 73)	P value
Demographics
Age (years), mean ± SD	48.7 ± 15.2	49.5 ± 15.3	47.3 ± 14.8	0.287
Male sex	143 (58.4)	97 (56.4)	46 (63.0)	0.327
Body mass index (kg/m²), mean ± SD	25.3 ± 4.1	25.5 ± 4.3	24.9 ± 3.8	0.302
Etiology
Biliary	123 (50.2)	89 (51.7)	34 (46.6)	0.452
Hypertriglyceridemic	53 (21.6)	35 (20.3)	18 (24.7)	0.437
Alcoholic	46 (18.8)	34 (19.8)	12 (16.4)	0.536
Others/idiopathic	23 (9.4)	14 (8.1)	9 (12.3)	0.298
Disease severity scores, mean ± SD
Acute Physiology and Chronic Health Evaluation II	9.1 ± 3.5	9.3 ± 3.6	8.8 ± 3.3	0.318
Ranson	3.2 ± 1.8	3.3 ± 1.9	3.0 ± 1.6	0.245
Sequential Organ Failure Assessment	2.8 ± 2.2	2.9 ± 2.3	2.5 ± 1.9	0.142
Laboratory parameters
WBC (× 109/L), mean ± SD	15.3 ± 4.7	15.5 ± 4.9	14.8 ± 4.3	0.293
Glucose (mmol/L), mean ± SD	9.7 ± 4.3	9.9 ± 4.5	9.3 ± 3.9	0.324
Serum amylase (U/L), mean ± SD	893 ± 567	914 ± 583	845 ± 526	0.381
Triglycerides in mmol/L, median (IQR)	3.5 (1.7-9.3)	3.6 (1.8-9.4)	3.3 (1.5-8.9)	0.415
C-reactive protein (mg/L), mean ± SD	138.2 ± 92.7	141.3 ± 94.5	131.2 ± 88.4	0.428
Interleukin-6 in pg/mL, median (IQR)	149.5 (76.3-257.8)	153.7 (79.2-264.3)	142.1 (71.5-241.6)	0.367
Intra-abdominal pressure (mmHg), mean ± SD	12.6 ± 4.7	12.8 ± 4.8	12.1 ± 4.4	0.294
Procalcitonin in ng/mL, median (IQR)	1.63 (0.68-3.47)	1.71 (0.72-3.52)	1.48 (0.61-3.31)	0.243
Severe acute pancreatitis	98 (40.0)	71 (41.3)	27 (37.0)	0.527

Data are presented as n (%). IQR: Interquartile range; SD: Standard deviation.