Intestinal ultrasound for monitoring postoperative Crohn’s disease: A systematic review and clinical implications

Table 2 Diagnostic performance of individual and combined intestinal ultrasound parameters and fecal calprotectin for detecting postoperative recurrence in Crohn’s disease, %

Ref.	Year	Parameter	Sensitivity	Specificity	PPV	NPV	Diagnostic accuracy	Comment
Furfaro et al[5]	2023	BWT ≥ 3 mm	77	65	81	59	73	Independent predictor of POR; OR = 2.43
		Mesenteric lymph nodes	35	97	95	43	56	Strong predictor; OR = 15.63
		FCP ≥ 50 μg/g	83	64	81	67	76	Independent predictor; OR = 8.58
		BWT ≥ 3 mm + FCP ≥ 50 μg/g	65	93	94	59	75	Best combined predictor
		BWT ≥ 3 mm + FCP ≥ 50 μg/g + LN+	33	100	100	59	66	Highest specificity; no false positives
Yebra Carmona et al[11]	2022	BWT > 3 mm + hyperemia	81	87	85	84	83	Strong correlation with endoscopy and FCP
		Hyperemia alone (grade ≥ 2)	67	74	70	72	71	Associated with endoscopic recurrence and FCP

BWT: Bowel wall thickness; FCP: Fecal calprotectin; LN+: Mesenteric lymph node enlargement; PPV: Positive predictive value; NPV: Negative predictive value; POR: Postoperative recurrence; OR: Odds ratio.