Correlation between inflammatory markers and disease severity in ulcerative colitis

Table 4 Performance of the multi-factor combined prediction model

Factor	AUC	95%CI	Sensitivity	Specificity	Optimal cutoff
IL-6 (pg/mL)	0.797	0.697-0.897	62.86%	95.12%	18.94
TNF-α (pg/mL)	0.820	0.735-0.905	65.71%	85.37%	24.85
CRP (mg/L)	0.763	0.662-0.863	74.29%	71.95%	14.32
Combined	0.917	0.861-0.972	88.57%	80.49%	0.26

AUC: Area under the curve; CI: Confidence interval; IL-6: Interleukin-6; TNF-α: Tumor necrosis factor-alpha; CRP: C-reactive protein.