Effectiveness of different appendiceal stump closure methods in laparoscopic appendectomy in children: A systematic review and network meta-analysis

doi:10.4240/wjgs.v17.i11.112182

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Nov 27, 2025; 17(11): 112182
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.112182

Table 4 League table comparing the overall complications, length of hospital stays, and operative time among the different appendiceal stump closure methods

		Endoloop	Endostapler	Harmonic Scalpel	LigaSure	Polymeric clip
The overall complications (risk ratios)	Endoloop	-	1.0397 (0.6691; 1.6153)	8.8503 (0.3772; 207.6631)	7.2308 (0.6721; 77.7929)	0.7207 (0.2305; 2.2532)
	Endostapler	-	-	8.5127 (0.3549; 204.1865)	6.9550 (0.6208; 77.9199)	0.6932 (0.2089; 2.3003)
	Harmonic scalpel	-	-	-	0.8170 (0.0157; 42.4231)	0.0814 (0.0043; 1.5439)
	LigaSure	-	-	-	-	0.0997 (0.0071; 1.3897)
	Polymeric clip	-	-	-	-	-
Length of hospital stays (mean difference)	Endoloop	-	-0.0025 (-0.5263; 0.5212)	0.8590 (-0.3280; 2.0460)	0.0000 (-0.9859; 0.9859)	0.1590 (-0.5422; 0.8603)
	Endostapler	-	-	0.8616 (-0.3413; 2.0645)	0.0025 (-1.1138; 1.1189)	0.1616 (-0.5663; 0.8895)
	Harmonic scalpel	-	-	-	-0.8590 (-2.4020; 0.6840)	-0.7000 (-1.6577; 0.2577)
	LigaSure	-	-	-	-	0.1590 (-1.0508; 1.3689)
	Polymeric clip	-	-	-	-	-
Operative time (mean difference)	Endoloop	-	2.7732 ( -1.9506; 7.4970)	13.5030 (1.4045; 25.6016)	9.6000 ( -0.4075; 19.6075)	4.1630 ( -2.3568; 10.6828)
	Endostapler	-	-	10.7299 ( -1.7110; 23.1707)	6.8268 ( -4.2395; 17.8932)	1.3899 (-5.7451; 8.5248)
	Harmonic scalpel	-	-	-	-3.9030 (-19.6041; 11.7981)	-9.3400 (-19.5315; 0.8515)
	LigaSure	-	-	-	-	-5.437 (-17.3809; 6.5070)
	Polymeric clip	-	-	-	-	-

Full Size Table

Citation: Elsayed WA, Elhadi SA, Gad D, Mohamed HM, Elsaid T, Omar MF, Almousa AA, Elkhouly A. Effectiveness of different appendiceal stump closure methods in laparoscopic appendectomy in children: A systematic review and network meta-analysis. World J Gastrointest Surg 2025; 17(11): 112182
URL: https://www.wjgnet.com/1948-9366/full/v17/i11/112182.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i11.112182

Elsayed WA, Elhadi SA, Gad D, Mohamed HM, Elsaid T, Omar MF, Almousa AA, Elkhouly A. Effectiveness of different appendiceal stump closure methods in laparoscopic appendectomy in children: A systematic review and network meta-analysis. World J Gastrointest Surg 2025; 17(11): 112182 [PMID: 41357644 DOI: 10.4240/wjgs.v17.i11.112182]

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