Effectiveness of different appendiceal stump closure methods in laparoscopic appendectomy in children: A systematic review and network meta-analysis

Table 2 Baseline characteristics of the included studies

Ref.	Intervention	Number	Number of boys	Age (years)	Cost	Follow-up
Akbiyik et al[24]	Polymeric clip	28	18	From 1 to 15	40 USD per two clips	1 week to 1 year
	Endoloop	21	14	From 3 to 15	121.5 USD per two endoloop
Akkoyun and Akbiyik[25]	Polymeric clip	121	67	From 3 to 15	10 USD for one clip	1-23 months
Escolino et al[12]	Endostapler	334	267	8.9	57.836 EUR for supplies	NA
	Endoloop	374	196	10.8	91.56 EUR for supplies
Juan et al[19]	LigaSure	209	116	9.7	NA	30 days
Kocaman et al[23]	LigaSure	94	51	12.5	NA	NA
	Endoloop	39	18	11.4
Martinez et al[14]	Polymeric Clip	17	10	10.06	35.36 USD total closure cost	30 days
	Surgical Stapler	90	50	11.95	375.67 USD total closure cost
Miyano et al[13]	Endostapler	81	48	10.8	1296 USD (anesthesia and one stapling set)	NA
	Endoloop	75	49	10.5	891 USD (anesthesia and 3 Loops)
Miyano et al[26]	Endostapler	31	13	9.7	Endostaple set at 550 USD	NA
	Endoloop	37	15	9.1	Endoloop at 48 USD
Naiditch et al[20]	Endostapler	391	223	9.92	NA	Median follow-up 15.5 days (range 0–51) for non-perforated; 19.3 days (range 0–135) for perforated
	Endoloop	388	233	9.69
Parikh et al[27]	Stapler	128	80	12	254.58 USD/stapler device	30 days
	Looped Suture	110	57	12.1	40.77 USD/unit
Pogorelić et al[22]	Polymeric Clip	197	119	11	NA	30 days
	Harmonic Scalpel	115	72	11
Pogorelić et al[21]	Polymeric clip	101	63	13	17.64 EUR	1-4 weeks
	Endoloop	176	84	13.5	34.16 EUR
Safavi et al[10]	Endostapler	24	NA	10.58	251.68 per ndostapler per case (in Canadian dollars)	NA
	Endoloop	208		11.55	57.57 per Endoloop per case (in Canadian dollars)
Zeineddin et al[9]	Stapler	35788	21677	10.7	10329.3 USD for all cases	30 days
	Endoloop	13403	8056	10.2	9569.2 USD for all cases