Endoscopic retrograde cholangiopancreatography for the management of biliary fistula following liver hydatid cyst related surgery or radiological interventions

Table 2 Univariate and multivariate analysis of variables associated with early leakage closure

Variable	Univariate analysis		Multivariate analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Gender
Male	1
Female	1.23 (0.53-2.87)	0.625
Size (cm)
> 9.4	1
< 9.4	1.19 (0.51-2.75)	0.683
Number of cyst
Single	1
Multiple	1.00 (0.38-2.60)	0.991
Garbi classification
1	1
2	1.40 (0.34-5.70)	0.639
3	0.63 (0.160-2.65)	0.530
4	0.571 (0.100-3.27)	0.530
ERCP intervention type
EST	1		1
EST + BD	4.58 (1.19-17.63)	0.027	5.27 (1.30-21.37)	0.020
Fistula flow rate
High	1		1
Low	3.11 (1.29-7.44)	0.011	3.43 (1.37-8.55)	0.008
ERCP complication
Present	1
Absent	1.108 (0.297-4.125)	0.879
Intervention type
PAIR	1
Surgery	1.11 (0.378-3.30)	0.841
Localization of leakage
Right intrahepatic	1
Left intrahepatic	1.13 (0.443-2.89)	0.794
Postoperative hospital stays (day)
> 5	1
< 5	1.0 (0.433-2.30)	1.000
ERCP time (day)
> 10	1
< 10	1.026 (0.441-2.38)	0.953

OR: Odds ratio; 95%CI: 95% confidence interval; ERCP: Endoscopic retrograde cholangiopancreatography; EST: Endoscopic sphincterotomy; BD: Balloon dilation; PAIR: Puncture, aspiration, injection, re-aspiration.