Factors influencing analysis of the efficacy of probiotics combined with enteral nutrition in postoperative patients with colorectal cancer

Table 6 Univariate logistic regression analysis of each influencing factor and efficacy

Factor	Coefficient	SE	Wald	P value	OR	CI lower	CI upper
Age (years)	0.046	0.011	4.074	< 0.001	1.047	1.025	1.071
ECOG performance status (0/≥ 1)	-0.539	0.242	2.228	0.026	0.583	0.361	0.935
TNM stage (≤ II/> II)	-0.402	0.180	2.233	0.026	0.669	0.469	0.951
Caloric intake (kcal/day)	-0.001	0.001	2.444	0.015	0.999	0.998	1.000
Protein intake (g/day)	-0.018	0.007	2.455	0.014	0.982	0.968	0.996
Fiber intake (g/day)	-0.040	0.018	2.243	0.025	0.961	0.928	0.995
DAO (U/L) postoperative day 7	0.371	0.150	2.468	0.014	1.448	1.082	1.951
I-FABP (μg/L) postoperative day 7	0.020	0.008	2.586	0.010	1.020	1.005	1.036
LPS (U/L) postoperative day 7	0.141	0.063	2.233	0.026	1.151	1.018	1.304
D-Lac (mg/L) postoperative day 7	0.115	0.049	2.343	0.019	1.122	1.02	1.237
Bifidobacterium postoperative day 7	-0.376	0.149	2.522	0.012	0.687	0.511	0.917
Fusobacterium nucleatum postoperative day 7	0.705	0.252	2.792	0.005	2.023	1.240	3.341
Lactobacillus postoperative day 7	-0.282	0.137	2.065	0.039	0.754	0.575	0.984
Bacteroides fragilis postoperative day 7	0.876	0.323	2.714	0.007	2.401	1.283	4.555
IgA (g/L) postoperative day 7	-0.407	0.163	2.503	0.012	0.666	0.482	0.913
IgM (g/L) postoperative day 7	-0.884	0.340	2.601	0.009	0.413	0.211	0.800
IgG (g/L) postoperative day 7	-0.158	0.050	3.157	0.002	0.854	0.773	0.941
CD4+/CD8+ postoperative day 7	-0.663	0.266	2.494	0.013	0.515	0.304	0.864
CRP (mg/L) postoperative day 7	0.075	0.034	2.183	0.029	1.078	1.008	1.154
TNF-α (ng/L) postoperative day 7	0.022	0.008	2.725	0.006	1.023	1.006	1.039
IL-6 (pg/mL) postoperative day 7	0.030	0.015	2.050	0.040	1.030	1.001	1.060

ECOG: Eastern Cooperative Oncology Group performance status; TNM: Tumor node metastasis; DAO: Diamine oxidase; I-FABP: Intestinal fatty acid binding protein; LPS: Lipopolysaccharide; D-Lac: D-lactate; IgM: Immunoglobulin M; IgG: Immunoglobulin G; IgA: Immunoglobulin A; CRP: C-reactive protein; TNF-α: Tumor necrosis factor-alpha; IL-6: Interleukin-6.