Predictive value of systemic immune-inflammation index and serum lactoferrin for postoperative survival in older patients with colon cancer

Table 7 Analysis results area under the curve area under the curve

Indicator	Cut-off value	Sensitivity (%)	Specificity (%)	AUC	95%CI	Youden's index
SII	650	78	71	0.75	0.68-0.82	0.49
LF	200	70	65	0.72	0.65-0.79	0.35
CRP	10	66	72	0.74	0.68-0.80	0.38
CEA	5	80	60	0.73	0.67-0.79	0.4
CA19-9	37	65	78	0.72	0.66-0.78	0.43

AUC: Area under the curve; SII: Systemic immune-inflammation index; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; CRP: C-reactive protein; LF: Lactoferrin.