Preoperative malignancy risk assessment in pancreatic cystic neoplasms using clinical and laboratory parameters

Table 3 Predictive values of independent predictors for malignancy or high-grade dysplasia at optimal cut-off values, n (%)/%

Parameters	Cut-off value1	Number2	Sensitivity	Specificity	PPV	NPV	OR (95%CI)
Age (years)	≥ 60	35 (50.0)	83.3	70.0	65.6	85.7	15.3 (3.8-61.9)
Red cell distribution width (%)	≥ 15.5	25 (35.7)	66.7	82.5	73.9	77.4	22.6 (5.2-97.8)

¹Cut-off values selected using Youden’s method to balance sensitivity and specificity.

²Number of patients above the given cut-off values.

PPV: Positive predictive value; NPV: Negative predictive value; OR: Odds ratio; CI: Confidence interval.