Fluid therapy strategies in acute pancreatitis: Randomized controlled trial comparing dextran and Ringer’s lactate

Table 1 Baseline characteristics of patients, mean ± SD/n (%)/median (interquartile range)

Type of solution	Intervention group, n = 55	Control group, n = 53	P value
Age in years	50.7 ± 13.2	51.9 ± 13.6	0.6
Male sex	42 (76.36)	41 (77.36)	1.0
Etiology			0.4
Alcohol	30 (54.55)	28 (52.83)
Gallstone	8 (14.55)	10 (18.87)
Metabolic	14 (25.45)	10 (18.87)
Others	3 (5.45)	5 (9.43)
Previous diabetes	7 (12.73)	8 (15.09)	0.9
History of smoking	25 (45.45)	18 (33.96)	0.3
Hematocrit as %	39.6 ± 6.0	39.6 ± 4.8	0.9
BUN in mg/dL	18 (13-25)	16 (12-21)	0.1
Serum creatinine in mg/dL	0.77 (0.60-0.90)	0.70 (0.58-0.89)	0.1
Albumin in g/dL	3.60 (3.34-4.00)	3.65 (3.50-4.10)	0.4
CTSI at 72 hours	3 (2-3)	3 (2-4)	0.2
BISAP score > 2	1 (0-1)	1 (0-1)	0.2
Marshal score	1 (0-1)	1 (0-1)	0.2
SOFA score	1 (1-3)	1 (1-3)	0.5
Severity of acute pancreatitis			0.7
Mild	12 (21.80)	14 (26.40)
Moderate	43 (78.20)	39 (73.60)
Volume of fluid resuscitation			0.4
At 24 hours	2500 (2000-2500)	2000 (2000-2500)
At 48 hours	4500 (4000-5000)	4000 (4000-4500)
At 72 hours	6500 (6000-7000)	6500 (6000-6500)
Total hospitalization costs (Euro)	1050 (853-1395)	1064 (885-1516)	0.2

BUN: Blood urea nitrogen; CTSI: Computed tomography severity index; BISAP: Bedside Index of Severity in Acute Pancreatitis; SOFA: Sequential Organ Failure Assessment.