Quantitative evaluation for preoperative clinical stage of colorectal cancer using dynamic contrast-enhanced magnetic resonance imaging

Table 6 Preoperative evaluation of volume transfer constant, rate constant, and extravascular extracellular volume fraction for N stage of colorectal cancer

Parameter	Cutoff value	AUC	SE	Sig	95%CI	Youden index	Specificity (%)	Sensitivity (%)
Ktrans (minute-1)	0.935 minute-1	0.773	0.072	0.002	0.633-0.914	0.530	72.00	81.00
Kep (minute-1)	2.470 minute-1	0.927	0.042	0.000	0.826-1.000	0.770	96.00	81.00
Ve (%)	0.585%	0.649	0.081	0.085	0.489-0.808	0.171	60.00	57.10

AUC: Area under the curve; SE: Standard error; Sig: Significance; CI: Confidence interval; Ktrans: Volume transfer constant; Kep: Rate constant; Ve: Extravascular extracellular volume fraction.