Quantitative evaluation for preoperative clinical stage of colorectal cancer using dynamic contrast-enhanced magnetic resonance imaging

Table 2 The diagnostic performance of volume transfer constant, rate constant, and extravascular extracellular volume fraction alone or as a combined tool for colorectal cancer

Parameter	Cutoff value	AUC	SE	Sig	95%CI	Youden index	Specificity (%)	Sensitivity (%)
Ktrans (minute-1)	0.905 minute-1	0.814	0.045	0.000	0.725-0.903	0.496	80.00	69.60
Kep (minute-1)	2.225 minute-1	0.765	0.051	0.000	0.665-0.866	0.396	70.00	69.60
Ve (%)	0.585%	0.795	0.048	0.000	0.701-0.889	0.497	97.50	52.20
Combine	-	0.863	0.043	0.000	0.779-0.947	0.726	90.00	82.60

Ktrans: Volume transfer constant; Kep: Rate constant; Ve: Extravascular extracellular volume fraction; AUC: Area under the curve; SE: Standard error; Sig: Significance; CI: Confidence interval.