Influencing factors and predictive model of the early postoperative recurrence of colorectal cancer with obstruction

Table 1 Univariate analysis of early postoperative recurrence in patients with colorectal cancer with obstruction

Characteristics	Relapse group (n = 52)	No-recurrent group (n = 129)	t/χ2 value	P value
Age (years)	62.55 ± 5.76	60.47 ± 8.49	1.621	0.107
BMI (kg/m2)	23.58 ± 2.04	23.96 ± 2.17	1.084	0.279
Gender			0.1401	0.708
Male	33 (63.46)	78 (60.47)
Female	19 (36.54)	51 (39.53)
Preoperative CEA (ng/mL)	9.78 ± 2.64	7.92 ± 1.87	5.346	< 0.001
Preoperative CA199 (U/mL)	27.26 ± 3.39	26.47 ± 3.01	1.540	0.125
Preoperative SII	387.65 ± 49.52	320.65 ± 38.68	9.699	< 0.001
Surgical method			1.8531	0.173
Radical resection	22 (42.31)	69 (53.49)
Palliative resection	30 (57.69)	60 (46.51)
Postoperative radiotherapy/chemotherapy			0.3801	0.539
Have	34 (65.38)	78 (60.47)
Not have	18 (34.62)	51 (39.53)
Obstruction site			0.5561	0.757
Right hemicolon	16 (30.77)	45 (34.88)
Left colon	19 (36.54)	40 (31.01)
Rectum	17 (32.69)	44 (34.11)
Obstruction types			1.7651	0.184
Complete obstruction	25 (48.08)	76 (58.91)
Incomplete obstruction	27 (51.92)	53 (41.09)
Tumor size (cm)	5.23 ± 1.39	4.95 ± 1.02	1.498	0.136
TNM stage			10.5792	0.004
Phase I	5 (9.62)	11 (8.52)
Phase II	10 (19.23)	57 (44.19)
Phase III	37 (71.15)	61 (47.29)
Degree of differentiation			9.4192	0.008
High	4 (7.69)	13 (10.08)
Moderately	11 (21.16)	56 (43.41)
Low	37 (71.15)	60 (46.51)
Pathological type			0.9151	0.339
Adenocarcinoma	25 (48.08)	52 (40.31)
Mucinous adenocarcinoma	27 (51.92)	77 (59.69)
Perineural invasion			4.3591	0.037
Have	29 (55.77)	50 (38.76)
Not have	23 (44.23)	79 (61.24)
MSI			3.6861	0.055
MSI-H	17 (32.69)	25 (19.38)
MSI-L/MSS	35 (67.31)	104 (80.62)
Ki-67 express (%)	36.43 ± 9.17	26.57 ± 6.63	8.065	< 0.001

¹Pearson χ².

²Fisher's exact test.

BMI: Body mass index; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; SII: Systemic immune-inflammation index; MSI: Tumor microsatellite instability; MSI-H: Refers to microsatellite high-frequency unstable tumors; MSI-L: Low frequency microsatellite instability tumor; MSS: Microsatellite stabilized tumors; TNM: Tumor, node, and metastasis.