Retrospective analysis of predictive factors for pathological complete response after neoadjuvant chemotherapy in gastric cancer

Table 2 Relationship between inflammatory indicators and pathological complete response in gastric cancer

Group	NLR	PLR	pCR rate (%)	P value	Clinical significance
Individual NLR analysis
Low NLR group	< 2.5	-	29.6	0.003	Significantly higher pCR
High NLR group	≥ 2.5	-	13.4	-	Lower pCR rate
Individual PLR analysis
Low PLR group	-	< 135	26.1	0.017	Significantly higher pCR
High PLR group	-	≥ 135	13.9	-	Lower pCR rate
Combined analysis
Optimal group	< 2.5	< 135	33.8	< 0.001	Highest pCR rate
Single low NLR	< 2.5	≥ 135	22.4	-	Intermediate pCR rate
Single low PLR	≥ 2.5	< 135	16.9	-	Intermediate pCR rate
Poor prognosis group	≥ 2.5	≥ 135	10.7	-	Lowest pCR rate

NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; pCR: Pathological complete response.