Enhanced recovery after surgery in gastric cancer surgery: Systematic review and meta-analysis of perioperative indwelling drainage tube use

Table 1 General information of the included studies

Ref.	Location	Intervention period	Study participants	Surgical method	Sample size	Intervention group	Control group	Outcome indicators
Kim et al[19], 2004	Korea	February 1, 2001-July 31, 2001	Gastric cancer patients	Total or subtotal gastrectomy with D2 or more lymph node dissection	I = 31, C = 21	FTS	Conventional care	1, 2, 13
Wang et al[20], 2019	China	March 1, 2016-October 31, 2016	Gastric cancer patients	Radical gastrectomy for gastric cancer	I = 30, C = 30	ERAS	Conventional care	1, 4, 6, 7, 8, 10, 11, 12, 13, 14
Kim et al[21], 2012	Korea	April 1, 2011-January 31, 2012	Gastric cancer patients	Laparoscopy-assisted radical gastrectomy with D2 Lymph node dissection	I = 22, C = 22	FTS	Conventional care	4, 9, 14
Abdikarim et al[22], 2015	China	June 1, 2010-December 31, 2012	Advanced gastric cancer patients	Laparoscopic surgery	I = 30, C = 31	ERAS	Conventional care	2, 3, 10, 13
Liu et al[23], 2016	China	September 1, 2014-August 31, 2015	Elderly gastric cancer patients	Laparoscopic surgery	I = 21, C = 21	FTS	Conventional care	1, 4, 5, 10, 11, 13, 14
Chen et al[24], 2012	China	January 1, 2009-May 31, 2011	Gastric cancer patients	Laparoscopy-assisted radical distal gastrectomy	I = 19, C = 22	FTS	Conventional care	5
Wu[25], 2018	China	December 1, 2015-August 31, 2017	Gastric cancer patients	Laparoscopic D2 radical gastrectomy	I = 34, C = 41	ERAS	Conventional care	1, 4, 9, 10, 13, 14
Chen[26], 2019	China	March 1, 2017-February 28, 2018	Advanced gastric cancer patients	D2 radical gastrectomy	I = 38, C = 37	ERAS	Conventional care	1, 4, 5, 9, 10, 12, 13, 14
Wu[27], 2019	China	June 1, 2016-June 30, 2017	Malignant gastric tumor patients	Total laparoscopic distal gastrectomy	I = 35, C = 35	ERAS	Conventional care	1, 4, 5, 9, 10, 11, 12, 13
Ma[28], 2019	China	January 1, 2018-January 31, 2019	Gastric cancer patients	Laparoscopic D2 radical gastrectomy	I = 40, C = 40	ERAS	Conventional care	4, 9, 11, 12
Wang[29], 2017	China	March 1, 2016-October 31, 2016	Gastric cancer patients	Radical gastrectomy for gastric cancer	I = 30, C = 30	ERAS	Conventional care	1, 4, 6, 8, 9, 10, 11, 12, 13, 14
Jiang et al[30], 2007	China	January 1, 2006-December 31, 2006	Gastric cancer patients	D2 radical resection	I = 40, C = 40	FTS	Conventional care	1, 4, 5, 9
Fan et al[31], 2019	China	April 1, 2017-May 31, 2018	Gastric cancer patients	Total gastrectomy or partial gastrectomy	I = 30, C = 30	FTS	Conventional care	1, 9, 11, 12
Li et al[32], 2016	China	July 1, 2013-February 28, 2015	Gastric adenocarcinoma patients	Laparoscopic radical gastrectomy	I = 67, C = 60	ERAS	Conventional care	1, 3, 4, 9, 12, 14
Chen[33], 2019	China	January 1, 2017-January 31, 2018	Gastric cancer patients	Laparoscopic surgery	I = 50, C = 50	FTS	Conventional care	1, 2, 4, 9, 10, 12, 13
Ruan et al[34], 2019	China	January 1, 2016-May 31, 2018	Gastric cancer patients	Laparoscopic radical gastrectomy	I = 65, C = 65	ERAS	Conventional care	1, 2, 9
Cheng[35], 2019	China	January 1, 2017-June 30, 2019	Gastric cancer patients	Laparoscopic radical gastrectomy	I = 29, C = 29	ERAS	Conventional care	1, 4, 6, 9, 10, 12, 13
Liu et al[36], 2018	China	May 1, 2015-July 31, 2017	Gastric cancer patients	Laparoscopic radical gastrectomy	I = 75, C = 74	ERAS	Conventional care	1, 2, 4, 8, 9, 10, 12, 14
Li and Huang[37], 2021	China	June 1, 2017-June 30, 2019	Gastric cancer patients	Laparoscopic radical gastrectomy	I = 41, C = 41	FTS	Conventional care	1, 4, 7, 10, 12
Miao[38], 2021	China	February 1, 2018-March 31, 2019	Gastric cancer patients	Laparoscopic D2 radical gastrectomy	I = 60, C = 60	ERAS	Conventional care	1, 4, 7, 9, 10, 11, 13
Liu and Li[39], 2021	China	March 1, 2017-May 31, 2020	Patients undergoing total gastrectomy for gastric cancer	Radical total gastrectomy	I = 43, C = 43	ERAS	Conventional care	4, 7, 8, 9, 12, 13

1: Time to first flatus; 2: Time to first defecation; 3: Time to first oral intake; 4: Time to ambulation; 5: Time to removal of abdominal drainage tube; 6: Time to recovery of bowel sounds; 7: Postoperative hospital stay; 8: Total hospital stay; 9: Incidence of total complications; 10: Incidence of anastomotic leakage; 11: Incidence of pulmonary infection; 12: Incidence of nausea and vomiting; 13: Incidence of surgical site infection; 14: Incidence of urinary tract infection; ERAS: Enhanced recovery after surgery; FTS: Fast-track surgery; I: Intervention group; C: Control group.