Association of serum hepatitis B surface antigen with hepatitis B virus DNA and hepatic function in patients with chronic hepatitis B

Figure 5 Optimal hepatitis B surface antigen cut-off values for high viral load and severe liver injury prediction. A: Receiver operating characteristic analysis of hepatitis B surface antigen (HBsAg) for predicting high viral load (hepatitis B virus-DNA ≥ 10⁵ IU/mL); B: Receiver operating characteristic analysis of HBsAg for detecting significant liver injury (alanine aminotransferase ≥ 2 × upper limit of normal).