Compound spleen-tonifying composition alleviates dextran sulfate sodium-induced ulcerative colitis in rats

doi:10.4240/wjgs.v17.i10.108239

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Oct 27, 2025; 17(10): 108239
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.108239

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Figure 3 Effect of compound spleen-tonifying composition and its extracts on the expression of tight junction protein in the colon of dextran sulfate sodium-induced rats. A and C: Zonula occludens-1 mRNA expression; B and D: Occludin mRNA expression; n = 8. ^aP < 0.05, dextran sulfate sodium (DSS) group vs control group; ^bP < 0.05, positive group vs DSS group; ^cP < 0.05, compound spleen-tonifying composition (CSTC) high dose group vs DSS group; ^dP < 0.05, CSTC medium dose group vs DSS group; ^eP < 0.05, ethyl acetate group vs DSS group; ^fP < 0.05, N-butanol vs DSS group. ZO-1: Zonula occludens-1; DSS: Dextran sulfate sodium; CSTC-H: Compound spleen-tonifying composition high dose; CSTC-M: Compound spleen-tonifying composition medium dose; CSTC-L: Compound spleen-tonifying composition low dose.

Citation: Zhao WC, Zhao QL, Zhang Y, Zhao N, Tian JQ, Wu YY, Zhang W. Compound spleen-tonifying composition alleviates dextran sulfate sodium-induced ulcerative colitis in rats. World J Gastrointest Surg 2025; 17(10): 108239
URL: https://www.wjgnet.com/1948-9366/full/v17/i10/108239.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i10.108239

Zhao WC, Zhao QL, Zhang Y, Zhao N, Tian JQ, Wu YY, Zhang W. Compound spleen-tonifying composition alleviates dextran sulfate sodium-induced ulcerative colitis in rats. World J Gastrointest Surg 2025; 17(10): 108239 [PMID: 41178872 DOI: 10.4240/wjgs.v17.i10.108239]

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