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Retrospective Study
©The Author(s) 2025.
World J Gastrointest Surg. Oct 27, 2025; 17(10): 106685
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.106685
Table 1 Comparison of definition and grading system for postoperative pancreatic fistula

The definition and grading system of postoperative pancreatic fistula in the 2005 ISGPF version
The ISGPS version of the definition and grading system for postoperative pancreatic fistula
ClassificationA-levelB-levelC-level
Clinical manifestationGoodGoodPoor
Special treatmentYesNoNo
Continuous ultrasound or CTNegativePositivePositive
Continuous drainage for > 3 weeksNoNoYes
Secondary surgeryNoNoYes
Pancreatic fistula related deathNoNoNo
Symptoms of infectionNoYesYes
SepsisNoNoYes
ReadmissionNoYesYes
Definition and classificationBiochemical leakageB-levelC-level
On the third day after surgery, the amylase value in the drainage fluid reached more than three times the normal upper limitYesYesYes
Peripancreatic continuous drainage > 3 weeksNoYesYes
Changes in clinically relevant treatment measures for pancreatic fistulaNoYesYes
Transcutaneous or intradermal microscopic puncture drainageNoYesYes
Angiographic intervention treatment of postoperative pancreatic fistula related bleedingNoYesYes
Secondary operationNoNoYes
Postoperative pancreatic fistula related symptoms of infectionNoWith (without organ failure)Yes
Postoperative pancreatic fistula related organs failureNoNoYes
Postoperative pancreas fistula related deathNoNoYes


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