Comparison of stereotactic body radiotherapy following transcatheter arterial chemoembolization vs transcatheter arterial chemoembolization alone in hepatocellular carcinoma

doi:10.4240/wjgs.v17.i10.105360

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Oct 27, 2025; 17(10): 105360
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.105360

Table 2 Post treatment outcomes among studied groups

Indicator	Group A	Group B	P value
CR (%)	54.5	75.0	0.012
PR (%)	36.4	15.0	0.008
SD (%)	9.1	7.0	0.045
Mean AFP after SBRT (ng/mL)	176.5 ± 35.0	18.4 ± 4.5	0.003
Mean ALP after SBRT (U/L)	120.0 ± 20.0	90.0 ± 15.0	0.007
Mean ALT after SBRT (U/L)	45.0 ± 10.0	30.0 ± 5.0	0.005
Mean AST after SBRT (U/L)	50.0 ± 12.0	35.0 ± 6.0	0.006
Mean GGT after SBRT (U/L)	60.0 ± 15.0	40.0 ± 8.0	0.004
Mean bilirubin after SBRT (mg/dL)	1.2 ± 0.3	0.8 ± 0.2	0.009
Mean platelets after SBRT (10³/μL)	200 ± 40	220 ± 30	0.021
Mean WBC after SBRT (10³/μL)	6.0 ± 1.0	5.5 ± 0.8	0.034
Mean hemoglobin after SBRT (g/dL)	12.0 ± 1.5	13.0 ± 1.0	0.015

CR: Complete response; PR: Partial response; SD: Stable disease; WBC: White blood cell; AFP: Alpha-fetoprotein; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; SBRT: Stereotactic body radiation therapy.

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Citation: Chen L, Wang L, Wang H. Comparison of stereotactic body radiotherapy following transcatheter arterial chemoembolization vs transcatheter arterial chemoembolization alone in hepatocellular carcinoma. World J Gastrointest Surg 2025; 17(10): 105360
URL: https://www.wjgnet.com/1948-9366/full/v17/i10/105360.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i10.105360

Chen L, Wang L, Wang H. Comparison of stereotactic body radiotherapy following transcatheter arterial chemoembolization vs transcatheter arterial chemoembolization alone in hepatocellular carcinoma. World J Gastrointest Surg 2025; 17(10): 105360 [PMID: 41178870 DOI: 10.4240/wjgs.v17.i10.105360]

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