Clinical significance of preoperative nutritional status in elderly gastric cancer patients undergoing radical gastrectomy: A single-center retrospective study

Table 4 Univariate Cox regression analyses of clinical factors associated with length of stay

Factor	LOS (days)	Hazard ratio (95%CI)	P value
Age (years)1			0.002
< 70	7 (7, 9)	1.000 (reference)
≥ 70	8 (7, 10)	1.620 (1.110-2.364)
Gender			0.076
Female	7 (7, 9)	1.000 (reference)
Male	8 (7, 10)	0.866 (0.568-1.319)
Nutritional status			0.134
Well-nourished	8 (7, 9)	1.000 (reference)
Malnourished	8 (7, 10)	0.652 (0.361-1.178)
Operation time (min)1			< 0.001
< 160	7 (7, 8)	1.000 (reference)
≥ 160	8 (7, 11)	2.307 (1.600-3.328)
Type of anesthesia			0.099
GA	8 (7, 11)	1.000 (reference)
TEA	8 (7, 9)	0.732 (0.432-1.238)
Type of surgery			0.055
Distal gastrectomy	7 (7, 9)	1.000 (reference)
Proximal gastrectomy	8 (7, 9)	0.611 (0.422-0.887)
Total gastrectomy	8 (7, 10)	0.510 (0.173-1.500)
Comorbidity			0.038
0-2	8 (7, 9)	1.000 (reference)
≥ 3	8 (7, 11)	2.415 (1.819-3.411)
BMI			0.088
≥ 20	8 (7, 10)	1.000 (reference)
< 20	8 (7, 9)	0.565 (0.294-1.089)
PNI1			0.005
≥ 44.5	8 (7, 11)	1.000 (reference)
< 44.5	10 (7, 11)	3.940 (1.042-7.904)
Albumin (g/L)			0.107
≥ 30	8 (7, 9)	1.000 (reference)
< 30	9 (8, 13)	1.087 (0.734-1.610)
Prealbumin (mg/L)			0.046
≥ 180	8 (7, 9)	1.000 (reference)
< 180	8 (7, 10)	1.265 (1.133-1.919)
Hemoglobin (g/L)			0.169
≥ 90	8 (7, 9)	1.000 (reference)
< 90	8 (7, 11)	1.418 (0.852-2.360)
Postoperative nutrition			0.337
Single transfusion	8 (7, 10)	1.000 (reference)
TNA	8 (7, 9)	0.826 (0.558-1.221)
Clavien-Dindo classification			< 0.001
None	8 (7, 9)	1.000 (reference)
I + II	10 (7, 12)	4.161 (2.199-7.876)
III or higher	10 (7, 17)	4.843 (2.771-8.464)

¹Split at median.

LOS: Length of stay; GA: General anesthesia; TEA: General anesthesia combined with thoracic epidural block; BMI: Body mass index; PNI: Prognostic nutritional index; TNA: Total nutrient admixture.