Neuroendocrine carcinoma of the common hepatic duct coexisting with distal cholangiocarcinoma: A case report and review of literature

doi:10.4240/wjgs.v16.i5.1449

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Gastrointest Surg. May 27, 2024; 16(5): 1449-1460
Published online May 27, 2024. doi: 10.4240/wjgs.v16.i5.1449

Table 2 Comparison of neuroendocrine-non-neuroendocrine neoplasm and pure neuroendocrine carcinoma in the extrahepatic biliary tract

	MiNEN	Pure NEC
Number of cases	19	29
Age, yr	70.47 ± 8.67	64.07 ± 14.88
Sex
Male	15	17
Female	4	12
Location
CHD	2	8
CBD	15	5
CHD + CBD	2	16
Symptom
Jaundice/pruritus	15	24
Abdominal pain	8	8
Anorexia/nauseas/vomit/fatigue/weight loss/ fever	9	3
Size, mm	26.63 ± 12.22	30.15 ± 15.08
Ki-67 index, %	62.12 ± 20.61	69.42 ± 20.75
Treatment
SR	17	12
SR + chemo/radio	2	12
Chemo/radio	0	2
Metastasis
Liver	7	9
Lymph node	0	8
Lung	3	2
Bone	1	3
Brain	0	3
Peritoneal/pleural/local	2	3

MiNEN: Mixed neuroendocrine-non-neuroendocrine neoplasm; NEC: Neuroendocrine carcinoma; CHD: Common hepatic duct; CBD: Common bile duct; SR: Surgical resection; Chemo: Chemotherapy; Radio: Radiotherapy.

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Citation: Chen F, Li WW, Mo JF, Chen MJ, Wang SH, Yang SY, Song ZW. Neuroendocrine carcinoma of the common hepatic duct coexisting with distal cholangiocarcinoma: A case report and review of literature. World J Gastrointest Surg 2024; 16(5): 1449-1460
URL: https://www.wjgnet.com/1948-9366/full/v16/i5/1449.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i5.1449

Chen F, Li WW, Mo JF, Chen MJ, Wang SH, Yang SY, Song ZW. Neuroendocrine carcinoma of the common hepatic duct coexisting with distal cholangiocarcinoma: A case report and review of literature. World J Gastrointest Surg 2024; 16(5): 1449-1460 [PMID: 38817298 DOI: 10.4240/wjgs.v16.i5.1449]

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