Nomogram model including LATS2 expression was constructed to predict the prognosis of advanced gastric cancer after surgery

Table 2 Unifactorial and multifactorial cox analysis

Characteristics	Univariate analysis				Multivariate analysis
	HR	95%CI	P value	HR		95%CI	P value
Sex
Male	Reference
Female	0.700	0.397-1.233	0.217
Age
< 65	Reference			Reference			0.199
≥ 65	6.632	4.026-10.926	< 0.001	1.780		0.739-4.286
Hypertension
No	1.202	0.800-1.812	0.378
Yes	Reference
Diabetes
Yes	1.256	0.608-2.594	0.537
No	Reference
Chronic lung disease
Yes	0.807	0.255-2.552	0.716
No	Reference
Smoking
Yes	0.900	0.604-1.312	0.605
No	Reference
Lymphatic invasion
Yes	13.121	7.840-21.959	< 0.001	3.251		1.519-6.960	0.002
No	Reference			Reference
LATS2
High	0.327	0.217-0.495	< 0.001	0.522		0.307-0.887	0.016
Low	Reference			Reference
Alcohol consumption
Yes	1.186	0.796-1.767	0.402
No	Reference
Tumor size
> 5 cm	Reference			Reference
≤ 5 cm	319.955	42.319-2419.010	< 0.001	79.564		8.657-731.251	< 0.001
T stage
2	Reference
3	6.691	2.407-18.598	< 0.001	9.620		3.390-27.300	< 0.001
4	5.452	2.372-12.536	< 0.001	4.156		1.753-9.850	< 0.001
N stage
0	Reference
1	1.650	0.824-3.304	0.158	1.762		0.872-3.563	0.115
2	2.237	1.186-4.220	0.013	2.248		1.155-4.376	0.017
3	4.332	2.452-7.653	< 0.001	3.874		2.127-7.056	< 0.001

HR: Hazard ratio.