Comparison of efficacy and safety of nab-paclitaxel and oxaliplatin + S-1 and standard S-1 and oxaliplatin chemotherapy regimens for treatment of gastric cancer

Table 4 Multi-factor Cox regression analysis

Variable	Z	HR (95%CI)	P value
RECIST 1.1
Ineffective		Reference
Effective	-2.544	0.507 (0.300-0.856)	0.011
TRG
Effective		Reference
Ineffective	2.518	1.949 (1.159-3.276)	0.012
Differentiation
Poorly		Reference
Moderate	-1.624	0.628 (0.358-1.101)	0.104
Well	-2.010	0.443 (0.200-0.980)	0.044
cT stage
2		Reference
3	1.263	1.520 (0.794-2.909)	0.206
4	1.834	2.041 (0.952-4.376)	0.067
cN stage
Negative		Reference
Positive	1.725	1.645 (0.934-2.895)	0.085
cTNM
II		Reference
III	1.383	1.575 (0.827-2.997)	0.167
IV	3.338	3.015 (1.577- 5.765)	0.001
Tumor diameter
≤ 2		Reference
2-5	2.131	2.503 (1.077-5.819)	0.033
≥ 5	2.736	3.281 (1.401-7.685)	0.006

RECIST: Response Evaluation Criteria in Solid Tumors; TRG: Tumor Regression Grade; HR: Hazard ratio.