Adjuvant chemotherapy for isolated resectable colorectal lung metastasis: A retrospective study using inverse probability treatment weighting propensity analysis

Table 1 Clinical, radiological, and histological characteristics of the population

Factors	Total, n (%)
Gender
Male	58 (60.4)
Female	38 (39.6)
Age at CRC diagnosis
Median (IQR)	59.7 (49.8-69.6)
Age at time of pulmonary surgery
Median (IQR)	62.6 (53-72.2)
Access
Open	20 (20.8)
VATS	76 (79.2)
Type of resection
Sublobar resection	54 (56.2)
Lobectomy	42 (43.8)
Adjuvant chemotherapy for PM
No	62 (64.6)
Yes	34 (35.4)
Primary tumor T stage
T1 or T2	8 (11.8)
T3 or T4	60 (88.2)
Primary tumor N stage
N0	28 (39.4)
N1 or N2	43 (60.6)
Primary tumor location
Left colon	29 (33.0)
Right colon	17 (19.3)
Rectum	42(47.7)
Adjuvant chemotherapy for CRC
No	30 (31.2)
Yes	66 (68.8)
CEA levels
≤ 5 ng/mL	47 (60.3)
> 5 ng/mL	31 (39.7)
Number of metastatic lesions
1	76 (79.2)
> 1	20 (20.8)
Tumor size (cm)
≤ 2 cm	51 (54.8)
> 2 cm	42 (45.2)
Prior extra-thoracic metastasis
No	86 (89.6)
Yes	10 (10.4)
CRC differentiation
Well/well to moderate	8 (11.8)
Moderate	57 (83.8)
Moderate to poor/poor	3 (4.4)
Smoking history
No	68 (70.8)
Yes	28 (29.2)
RAS
Wild type	10 (62.5)
mutant type	6 (37.5)
Bilateral pulmonary nodules
No	91 (94.8)
Yes	5 (5.2)
LN sampling at PM
No	51 (53.1)
Yes	45 (46.9)
Positive LN at PM
No	90 (93.8)
Yes	6 (6.2)

CRC: Colorectal cancer; CEA: Carcinoembryonic antigen; LN: Lymph nodes; PM: Pulmonary metastases; RAS: Rat sarcoma; VATS: Video-assisted thoracoscopic surgery; DFI: Disease-free interval; IQR: Interquartile range.