Risk factors for recurrence of common bile duct stones after surgical treatment and effect of ursodeoxycholic acid intervention

doi:10.4240/wjgs.v16.i1.103

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Jan 27, 2024 (publication date) through May 14, 2024

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Gastrointest Surg. Jan 27, 2024; 16(1): 103-112
Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.103

Table 1 Patient characteristics

Variable		Total (n = 100)	Control (n = 47)	UDCA (n = 53)
Age (yr), median (P₂₅, P₇₅)		53.00 (48, 60)	51 (47, 60)	54 (48.5, 60)
Gender, n (%)	Male	44 (44)	21 (44.68)	23 (23.40)
	Female	56 (56)	26 (55.32)	30 (56.60)
Jaundice, n (%)	Yes	27 (27)	12 (25.53)	15 (28.30)
	No	73 (73)	35 (74.47)	38 (71.70)
Hypertension, n (%)	Yes	25 (25)	12 (25.53)	14 (26.42)
	No	75 (75)	35 (74.47)	39 (73.58)
Diabetes, n (%)	Yes	32 (32)	14 (29.79)	18 (33.96)
	No	68 (68)	33 (70.21)	35 (66.04)
History of biliary tract surgery, n (%)	Yes	14 (14)	6 (12.77)	8 (15.09)
	No	86 (86)	41 (87.23)	45 (84.91)
Parapillary diverticulum, n (%)	Yes	36 (36)	23 (48.94)	13 (24.53)
	No	64 (64)	24 (51.06)	40 (75.47)
No. of stones, n (%)	≤ 3	49 (49)	25 (53.19)	24 (45.28)
	> 3	51 (51)	22 (46.81)	29 (54.72)
Bile culture positive, n (%)		37 (37)	20 (42.55)	17 (32.08)
Common bile duct diameter (mm), median (P₂₅, P₇₅)		14.00 (13.00, 16.00)	15.0 (13.0, 16.0)	14.0 (12.0, 16.0)
Maximum stone diameter (mm), median (P₂₅, P₇₅)		13.00 (12.00, 15.00)	13.0 (12.0, 15.0)	13.0 (11.5, 14.5)
ERCP time (min), median (P₂₅, P₇₅)		64.00 (61.00, 68.00)	63 (61, 67)	64 (61, 71)
WBC (10⁹/L, mean ± SD)		6.60 ± 0.96	6.24 ± 1.24	6.60 ± 0.97
PCT (ng/mL), median (P₂₅, P₇₅)		0.18 (0.12, 0.27)	0.17 (0.12, 0.25)	0.18 (0.13, 0.28)

UDCA: Ursodeoxycholic acid; ERCP: Endoscopic retro-grade cholangiopancreatography; WBC: White blood cell; PCT: Procalcitonin.

Citation: Yuan WH, Zhang Z, Pan Q, Mao BN, Yuan T. Risk factors for recurrence of common bile duct stones after surgical treatment and effect of ursodeoxycholic acid intervention. World J Gastrointest Surg 2024; 16(1): 103-112
URL: https://www.wjgnet.com/1948-9366/full/v16/i1/103.htm
DOI: https://dx.doi.org/10.4240/wjgs.v16.i1.103