Comparison between upfront surgery and neoadjuvant chemotherapy in patients with locally advanced gastric cancer: A systematic review

Table 5 R0 resection rate of gastric cancer in patients after neoadjuvant chemotherapy and surgery versus upfront surgery

Ref.	R0 resection rate		P value
	NAT	US
Ahn et al[8], 2014	92.2%
Biondi et al[9], 2018	82.9%	83.6%	0.449
Bracale et al[10], 2021	NS	NS
Eom et al[11], 2018	97.7%	97.7%
Feng et al[12], 2015	95%	94.4%
Wang et al[13], 2021	84.6%	56.7%	0.029
Xue et al[14], 2018	100%	96%
Kang et al[15], 2021	NS	NS
Kano et al[16], 2019	100%	100%
Lin et al[17], 2022	90.1%
Marino et al[18], 2021	NS	NS
Molina et al[19], 2013	-	80%
Pardo et al[20], 2020	NS	NS
Wang et al[21], 2019	89.2%	84.6%	> 0.05
Wang et al[22], 2021	96%1	89%1	0.061
Wu et al[23], 2019	NS	NS
Xu et al[24], 2021	94.12%	89.14%	0.072
Zhao et al[25], 2017	NS	NS

¹Neoadjuvant chemoratdiotherapy versus neoadjuvant chemotherapy (96% vs 89%, P = 0.06).

NAT: Neoadjuvant chemotherapy; US: Upfront surgery; NS: Not stated.