Prognostic scores in primary biliary cholangitis patients with advanced disease

doi:10.4240/wjgs.v15.i8.1774

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Aug 27, 2023; 15(8): 1774-1783
Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1774

Table 2 Discriminative performance of the various risk prediction scores calculated at baseline and after 1 year of ursodeoxycholic acid therapy

C-statistic at various follow-up time points (95%CI)
Risk prediction model	Baseline	1 yr of UDCA
GLOBE		0.731 (0.681-0.782)
UK-PBC		0.727 (0.678-0.776)
APRI	0.592 (0.536-0.647)	0.347 (0.296-0.398)
FIB4	0.648 (0.593-0.704)	0.680 (0.628-0.732)
ALBI	0.705 (0.656-0.755)	0.725 (0.672-0.778)
Mayo	0.702 (0.653-0.751)	0.740 (0.690-0.791)

ALBI: Albumin-bilirubin; APRI: Aspartate aminotransferase-to-platelet ratio index; C-statistic: Concordance statistic; CI: Confidence interval; FIB4: Fibrosis-4 index; UDCA: Ursodeoxycholic acid.

Citation: Feng J, Xu JM, Fu HY, Xie N, Bao WM, Tang YM. Prognostic scores in primary biliary cholangitis patients with advanced disease. World J Gastrointest Surg 2023; 15(8): 1774-1783
URL: https://www.wjgnet.com/1948-9366/full/v15/i8/1774.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i8.1774