Radiation therapy prior to a pancreaticoduodenectomy for adenocarcinoma is associated with longer operative times and higher blood loss

doi:10.4240/wjgs.v15.i8.1663

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Aug 27, 2023; 15(8): 1663-1672
Published online Aug 27, 2023. doi: 10.4240/wjgs.v15.i8.1663

Table 3 Thirty-day postoperative complications for patients with adenocarcinoma of the pancreas undergoing a pancreaticoduodenectomy from 2015 to 2019, n (%)

Complication	Initial surgery	Neoadjuvant radiation	P value
Complication	n = 9988	n = 1470	P value
Wound dehiscence	110 (1.1)	16 (1.1)	0.965
Ventilator dependent > 48 h	223 (2.2)	38 (2.6)	0.398
Stroke	29 (0.3)	3 (0.2)	0.791
Myocardial infarction	124 (1.2)	9 (0.6)	0.035^a
DVT	269 (2.7)	55 (3.7)	0.024^a
Pulmonary embolism	108 (1.1)	5 (0.3)	0.004^a
Pneumonia	305 (3.1)	30 (2.0)	0.031^a
UTI	247 (2.5)	32 (2.2)	0.491
Septic shock	207 (2.1)	34 (2.3)	0.545

^aP < 0.05.

DVT: Deep venous thrombosis; UTI: Urinary tract infection.

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Citation: Aploks K, Kim M, Stroever S, Ostapenko A, Sim YB, Sooriyakumar A, Rahimi-Ardabily A, Seshadri R, Dong XD. Radiation therapy prior to a pancreaticoduodenectomy for adenocarcinoma is associated with longer operative times and higher blood loss. World J Gastrointest Surg 2023; 15(8): 1663-1672
URL: https://www.wjgnet.com/1948-9366/full/v15/i8/1663.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i8.1663

Aploks K, Kim M, Stroever S, Ostapenko A, Sim YB, Sooriyakumar A, Rahimi-Ardabily A, Seshadri R, Dong XD. Radiation therapy prior to a pancreaticoduodenectomy for adenocarcinoma is associated with longer operative times and higher blood loss. World J Gastrointest Surg 2023; 15(8): 1663-1672 [PMID: 37701691 DOI: 10.4240/wjgs.v15.i8.1663]

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