Radiation therapy prior to a pancreaticoduodenectomy for adenocarcinoma is associated with longer operative times and higher blood loss

Table 3 Thirty-day postoperative complications for patients with adenocarcinoma of the pancreas undergoing a pancreaticoduodenectomy from 2015 to 2019, n (%)

Complication	Initial surgery	Neoadjuvant radiation	P value
	n = 9988	n = 1470
Wound dehiscence	110 (1.1)	16 (1.1)	0.965
Ventilator dependent > 48 h	223 (2.2)	38 (2.6)	0.398
Stroke	29 (0.3)	3 (0.2)	0.791
Myocardial infarction	124 (1.2)	9 (0.6)	0.035a
DVT	269 (2.7)	55 (3.7)	0.024a
Pulmonary embolism	108 (1.1)	5 (0.3)	0.004a
Pneumonia	305 (3.1)	30 (2.0)	0.031a
UTI	247 (2.5)	32 (2.2)	0.491
Septic shock	207 (2.1)	34 (2.3)	0.545

^aP < 0.05.

DVT: Deep venous thrombosis; UTI: Urinary tract infection.