Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma: A multicenter study

doi:10.4240/wjgs.v15.i7.1340

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Jul 27, 2023; 15(7): 1340-1353
Published online Jul 27, 2023. doi: 10.4240/wjgs.v15.i7.1340

Table 2 Pretransplant treatments, n (%)

	Before PSM			After PSM
	HCC (n = 141)	cHCC-CC (n = 111)	P value	HCC (n = 70)	cHCC-CC (n = 70)	P value
Locoregional therapy prior to LT	112 (79.4)	74 (66.7)	0.03	50 (71.4)	52 (74.3)	0.849
TACE	102 (72.3)	65 (58.6)	0.023	45 (64.3)	46 (65.7)	0.859
Liver resection	24 (17.0)	20 (18.0)	0.868	10 (14.3)	14 (20.0)	0.502
RFA	46 (32.6)	17 (15.3)	0.002	17 (24.3)	12 (17.1)	0.404
Radiation therapy	13 (9.2)	8 (7.2)	0.65	6 (8.6)	6 (8.6)	0.618
Number of locoregional therapies before LT > 3	56 (39.7)	34 (30.6)	0.147	27 (38.6)	26 (37.1)	0.862
AFP > 20 ng/mL	37 (26.2)	56 (50.5)	< 0.001	23 (32.9)	25 (35.7)	0.859
PIVKA-II > 40 mAU/mL	50 (35.5)	40 (39.2)	0.591	30 (42.9)	19 (30.2)	0.152

LT: Liver transplantation; TACE: Transarterial chemoembolization; RFA: Radiofrequency ablation; AFP: Alpha-fetoprotein; PIVKA-II prothrombin-induced by vitamin K absence-II; HCC: Hepatocellular carcinoma; PSM: Propensity score matching; cHCC-CC: Combined hepatocellular carcinoma and cholangiocarcinoma.

Citation: Kim J, Joo DJ, Hwang S, Lee JM, Ryu JH, Nah YW, Kim DS, Kim DJ, You YK, Yu HC. Liver transplantation for combined hepatocellular carcinoma and cholangiocarcinoma: A multicenter study. World J Gastrointest Surg 2023; 15(7): 1340-1353
URL: https://www.wjgnet.com/1948-9366/full/v15/i7/1340.htm
DOI: https://dx.doi.org/10.4240/wjgs.v15.i7.1340