Fascia- vs vessel-oriented lateral lymph node dissection for rectal cancer: Short-term outcomes and prognosis in a single-center experience

Table 4 Univariable and multivariable Cox regression analyses of progression-free survival of the entire cohort (n = 105)

	Univariable		Multivariable
	HR (95%CI)	P value	HR (95%CI)	P value
LLND method
Vessel–oriented LLND	Reference		Reference
Fascia–oriented LLND	1.17 (0.51 - 2.68)	0.709	1.16 (0.51–2.66)	0.729
Age
< 65	Reference		—
≥ 65	1.20 (0.47 - 3.07)	0.706	—
Sex
Male	Reference		—
Female	0.7 (0.31-1.55)	0.374	—
p/yp tumor stagea
0–II	Reference		Reference
III	2.99 (1.02–8.76)	0.045	3.16 (1.04–9.60)	0.042
Pathological LLN
Negative	Reference		Reference
Positive	0.83 (0.33 - 2.12)	0.703	0.83 (0.31–2.22)	0.714
Adjuvant therapy
No	Reference		—
Yes	2.08 (0.62-7.02)	0.239	—

^aThe pathological tumor stage was based on the eighth edition of the American Joint Committee on Cancer TNM staging system.

LLND: Lateral lymph node dissection; LLN: Lateral lymph nodes; HR: Hazard ratio.