Fascia- vs vessel-oriented lateral lymph node dissection for rectal cancer: Short-term outcomes and prognosis in a single-center experience

Table 3 Univariable and multivariable Cox regression analyses of overall survival of the entire cohort (n = 105)

	Univariable		Multivariable
	HR (95%CI)	P value	HR (95%CI)	P value
LLND method
Vessel–oriented LLND	Reference		Reference
Fascia–oriented LLND	0.95 (0.36–2.50)	0.918	0.94 (0.35–2.48)	0.893
Age
< 65	Reference		—
≥ 65	2.56 (0.87–7.51)	0.088	—
Sex
Male	Reference		—
Female	0.78 (0.30–2.06)	0.621	—
p/yp tumor stagea
0–II	Reference		Reference
III	9.98 (1.32–75.55)	0.026	9.66 (1.25–74.66)	0.030
Pathological LLN
Negative	Reference		Reference
Positive	1.82 (0.64–5.18)	0.264	1.14 (0.39–3.31)	0.807
Adjuvant therapy
No	Reference		—
Yes	—	0.202	—

^aThe pathological tumor stage was based on the eighth edition of the American Joint Committee on Cancer TNM staging system.

LLND: Lateral lymph node dissection; LLN: Lateral lymph nodes; HR: Hazard ratio.