Clinical features of acute esophageal mucosal lesions and reflux esophagitis Los Angeles classification grade D: A retrospective study

Table 3 Comorbidities at onset, n (%)

	AEML (n = 105)		RE-D (n = 48)	Risk ratio (95%CI)	P value
	Black esophagus (n = 19)	Non-black esophagus (n = 86)
Comorbidities	61 (57.5)		9 (18.8)	3.10 (1.68–5.71)	< 0.001
Infection	23 (21.7)		5 (10.4)
	3 (15.8)	20 (23.0)
Treatment for malignancy	9 (8.5)		0 (0.0)
	4 (21.1)	5 (5.7)
Prerenal failure	8 (7.5)		1 (2.1)
	1 (5.3)	7 (8.0)
After surgery	7 (6.6)		1 (2.1)
	1 (5.3)	6 (6.9)
Stroke	4 (3.8)		1 (2.1)
	0 (0.0)	4 (4.6)
Alcoholic ketoacidosis	4 (3.8)		0 (0.0)
	0 (0.0)	4 (4.6)
Diabetic ketoacidosis/Hyperosmolar hyperglycemic syndrome	2 (1.9)		0 (0.0)
	1 (5.3)	1 (1.1)
Pulmonary embolism	1 (0.9)		0 (0.0)
	0 (0.0)	1 (1.1)
Peripheral arterial disease	1 (0.9)		0 (0.0)
	0 (0.0)	1 (1.1)
Duodenal ulcer	1 (0.9)		0 (0.0)
	0 (0.0)	1 (1.1)
Liver disease	1 (0.9)		0 (0.0)
	1 (5.3)	0 (0.0)
Heart failure	0 (0.0)		1 (2.1)
	0 (0.0)	0 (0.0)

AEML: Acute esophageal mucosal lesion; RE-D: Reflux esophagitis Los Angeles classification grade D; 95%CI: 95% confidence interval.