Risk factors for anastomotic fistula development after radical colon cancer surgery and their impact on prognosis

Table 7 Linear regression of Functional Assessment of Cancer Therapy–Colorectal anastomotic fistula after radical colon cancer surgery

Related factor	B	SE	t value	P value
Anastomotic fistula	-11.180	2.506	-4.461	0.000
Surgery method	0.060	3.204	0.019	0.985
Age (yr)	-0.148	0.049	-3.012	0.003
Gender	0.221	1.155	0.191	0.848
Hypertension	0.383	1.183	0.323	0.747
Diabetes	-3.292	1.348	-2.443	0.015
Site of lesion	-0.172	0.765	-0.224	0.823
Type of organization	-0.172	1.288	-0.134	0.894
Type of TNM	-2.414	1.322	-1.826	0.069
Lymph node metastasis	-2.694	1.286	-2.094	0.037
Preoperative adjuvant chemotherapy	-0.196	1.511	-0.130	0.897
Post-operative ICU stay	0.480	2.665	0.180	0.857
Type of pathology	-6.303	1.322	-4.768	0.000
Operating time (min)	0.040	0.036	1.116	0.265
Intraoperative bleeding (mL)	-0.014	0.024	-0.572	0.567
Post-operative time to exhaustion (d)	0.731	0.748	0.977	0.329
Postoperative hospitalization time (d)	-0.242	0.270	-0.894	0.372
Preoperative CEA (ng/mL)	0.912	0.709	1.287	0.199
Postoperative CEA (ng/mL)	-1.778	0.782	-2.274	0.023
Preoperative CA125 (U/mL)	0.488	0.170	2.865	0.004
Postoperative CA125 (U/mL)	-0.416	0.178	-2.333	0.020
Preoperative Alb (g/L)	0.077	0.158	0.490	0.624
Postoperative Alb (g/L)	0.381	0.209	1.818	0.070
Preoperative TP (g/L)	0.020	0.178	0.114	0.910
Postoperative TP (g/L)	0.018	0.168	0.108	0.914
Preoperative Hb (g/L)	0.060	0.132	0.455	0.649
Postoperative Hb (g/L)	-0.068	0.131	-0.523	0.601
Preoperative K (mmol/L)	0.244	3.504	0.070	0.945
Postoperative K (mmol/L)	0.437	1.239	0.353	0.724

SE: Standard error; TNM: Tumor node metastasis; ICU: Intensive care unit; CEA: Carcinoembryonic antigen; CA125: Carbohydrate antigen; Alb: Albumin; TP: Total protein; Hb: Hemoglobin; K: Kalium.