Risk factors for anastomotic fistula development after radical colon cancer surgery and their impact on prognosis

Table 1 Comparison of clinical features of patients after radical colon cancer surgery

Item, n (%)	Anastomotic fistula group	Non-anastomotic fistula group	t/χ2	P value
Gender
Male	19 (50.0)	236 (52.4)	0.084	0.772
Female	19 (50.0)	214 (47.6)
Age (yr)	58.95 ± 11.91	52.90 ± 12.7	-2.921	0.004
Hypertension or not
Yes	17 (44.7)	171 (38.0)	0.672	0.413
No	21 (55.3)	279 (62.0)
Diabetes or not
Yes	16 (42.1)	110 (24.4)	5.706	0.017
No	22 (57.9)	340 (75.6)
Site of lesion
Left hemi-colon	17 (44.7)	227 (50.4)	0.892	0.640
Right hemi-colon	15 (39.5)	144 (25.3)
Transverse colon	6 (15.8)	79 (17.6)
Type of organization
Low to moderately differentiated adenocarcinoma	27 (71.1)	325 (72.2)	0.024	0.877
Highly differentiated adenocarcinoma	11 (28.9)	125 (27.8)
Type of TNM
Type of I-II	20 (52.6)	323 (71.8)	6.151	0.013
Type of III	18 (47.4)	127 (28.2)
Surgery method
Laparoscopic radical surgery	9 (23.7)	278 (61.8)	20.991	0.000
Traditional radical surgery	29 (76.3)	172 (38.2)
Lymph node metastasis or not
Yes	11 (28.9)	122 (27.1)	0.060	0.807
No	27 (71.1)	328 (72.9)
With preoperative adjuvant chemotherapy or not
Yes	13 (34.2)	85 (18.9)	5.125	0.024
No	25 (65.8)	365 (81.1)
Post-operative ICU stay
Yes	5 (13.2)	20 (4.4)	5.474	0.019
No	33 (86.8)	430 (95.6)
Type of pathology
Ductal gland	30 (78.9)	332 (73.8)	0.489	0.484
Mucus gland	8 (21.1)	118 (26.2)

TNM: Tumor node metastasis; ICU: Intensive care unit.