Correlation between the expressions of metastasis-associated factor-1 in colon cancer and vacuolar ATP synthase

Table 2 The relationship between the expression of metastasis-associated factor-1, vacuolar ATP synthase and clinicopathological features of colon cancer

Clinicopathologcal features	Cases	MACC1 positive expression (%)	χ2	P value	V-ATPase positive expression (%)	χ2	P value
Age (years)
≤ 55 years old	54	33 (61.11)	0.538	0.463	35 (64.81)	0.317	0.573
> 55 years old	50	34 (68.00)			35 (70.00)
Gender
Male	56	35 (62.50)	0.196	0.658	40 (71.43)	0.936	0.333
Female	48	32 (66.67)			30 (62.50)
Tumor site
Left colon	50	32 (64.00)	0.008	0.931	36 (72.00)	0.964	0.326
Right colon	54	35 (64.81)			34 (62.96)
TNM staging
Phase Ⅰ-Ⅱ	65	34 (52.31)	11.101	0.001	35 (53.85)	14.275	0.000
Phase Ⅲ	39	33 (84.62)			35 (89.74)
Degree of differentiation
High differentiation	31	12 (38.71)	12.74	0.000	11 (35.48)	20.327	0.000
Medium and low differentiation	73	55 (75.34)			59 (80.82)
Lymph node metastasis
Yes	49	40 (81.63)	11.973	0.001	42 (85.71)	14.266	0.000
No	55	27 (49.09)			28 (50.91)
Vascular infiltration
Yes	41	24 (58.54)	1.023	0.312	26 (63.41)	0.466	0.496
No	63	43 (68.25)			44 (69.84)
Nervous system infiltration
Yes	32	22 (68.75)	0.378	0.539	21 (65.63)	0.059	0.807
No	72	45 (62.50)			49 (68.06)
Tumor diameter
> 5 cm	60	46 (76.67)	9.276	0.002	40 (66.67)	0.026	0.871
≤ 5 cm	44	21 (47.73)			30 (68.18)

MACC1: Metastasis-associated factor-1; V-ATPase: Vacuolar ATP synthase.