Predicting lymph node metastasis in colorectal cancer: An analysis of influencing factors to develop a risk model

Table 3 Coefficients and odds ratios of the predictors in the final model

Predictor	Coefficient	Odds ratio	P value
Age (yr)	0.02	1.02	0.01a
Tumor location			< 0.001b
Right colon	Reference	Reference
Left colon	-0.65	0.52
Rectum	-1.04	0.35
Tumor size	0.17	1.19	< 0.001a
Tumor differentiation	-0.48	0.62	0.02a
Tumor invasion depth			< 0.001b
Tis	Reference	Reference
T1	1.32	3.74
T2	2.12	8.34
T3	3.45	31.49
T4a	4.67	106.71
T4b	5.89	361.23
Lymphovascular invasion	1.23	3.42	< 0.001a
Perineural invasion	1.01	2.75	< 0.001a
Tumor budding	0.87	2.38	< 0.001a
Frequency of cluster 1	0.05	1.05	< 0.001a
Frequency of cluster 2	-0.04	0.96	0c
Frequency of cluster 3	0.03	1.03	0.02a
Frequency of cluster 4	-0.02	0.98	0.04a
Frequency of cluster 5	0.04	1.04	0.01a
Frequency of cluster 6	-0.03	0.97	0.03a
Frequency of cluster 7	0.02	1.02	0.05a
Frequency of cluster 8	-0.01	0.99	0.06c
Frequency of cluster 9	0.01	1.01	0.07c
Frequency of cluster 10	-0.01	0.99	0c

^aP < 0.05, statistically significant.

^bP < 0.001, highly statistically significant.

^cP > 0.05, not statistically significant.