Gene polymorphisms associated with sudden decreases in heart rate during extensive peritoneal lavage with distilled water after gastrectomy

Table 4 Comparison of genotype and allele frequencies of single nucleotide polymorphisms in patients with ≥ 15% vs < 15% heart rate variability, n (%)

SNP	HRV ≥ 15%	HRV < 15%	χ2	P value	OR (95%CI)
TEP1 (rs938886)			1.56	0.46
GG	30 (33.33)	60 (66.67)			1.00 (Reference)
GC	34 (40.00)	51 (60.00)			1.34 (0.72, 2.52)
CC	8 (47.06)	9 (52.94)			1.74 (0.59, 5.15)
			1.50	0.22
G	94 (35.47)	171 (64.53)			1.00 (Reference)
C	50 (42.02)	69 (57.98)			1.30 (0.83, 2.04)
TEP1 (rs1713449)			2.02	0.36
CC	29 (32.58)	60 (67.42)			1.00 (Reference)
CT	34 (40.48)	50 (59.52)			1.42 (0.75, 2.67)
TT	9 (47.37)	10 (52.63)			1.85 (0.66, 5.21)
			2.00	0.16
C	92 (35.11)	170 (64.89)			1.00 (Reference)
T	52 (42.62)	70 (57.38)			1.36 (0.87, 2.13)
RECQL5 (rs820196)			6.20	0.045
TT	27 (31.03)	60 (68.97)			1.00 (Reference)
TC	40 (47.06)	45 (52.94)			1.97 (1.05, 3.70)a
CC	5 (25.00)	15 (75.00)			0.69 (0.22, 2.13)
			0.49	0.48
T	94 (36.29)	165 (63.71)			1.00 (Reference)
C	50 (40.00)	75 (60.00)			1.15 (0.74, 1.78)

^aP < 0.05 vs TT.

Logistic regression analyses adjusting for age, gender, smoking, hypertension, and thyroid function. Two covariates with missing values were dropped. SNP: Single nucleotide polymorphism; TEP1: Telomerase-associated protein 1; HRV: Heart rate variability; OR: Odds ratio; CI: Confidence interval; RECQL5: RecQ like helicase 5.