Impact of comorbid renal dysfunction in patients with hepatocellular carcinoma on long-term outcomes after curative resection

Table 5 Postoperative complications in the patients with and without renal dysfunction

	CKD stage		P value
	RD (EGFR < 60), n = 128	Non-RD (EGFR ≥ 60), n = 672
All complications	33 (25.8)	169 (25.1)	0.96
Major complication (Grade ≥ 2)	20 (15.6)	112 (16.7)	0.91
Bile leakage	12 (9.8)	44 (6.5)	0.33
Ascites	6 (4.7)	27 (4.0)	0.90
Pleural effusion	4 (3.1)	37 (5.5)	0.41
Pneumonia	6 (5.3)	12 (1.8)	0.70
Bleeding	7 (5.5)	12 (1.8)	< 0.05
Liver failure	1 (0.8)	9 (1.3)	0.55
Surgical site infection	5 (3.9)	12 (1.8)	< 0.05
Duration of postoperative hospital stay (d)	16.0 ± 14.5	16.0 ± 19.3	0.17
Died during hospitalization	11 (0.8)	12 (0.1)	0.96

¹One patient in the renal dysfunction group died due to postoperative gastrointestinal perforation and an intraabdominal abscess.

²One patient in the non-renal dysfunction group died due to postoperative liver failure.

P values were determined by the χ² test or the Mann-Whitney U test. RD: Renal dysfunction; CKD: Chronic kidney disease; EGFR: Estimated glomerular filtration rate.