Prognostic factors for patients with mass-forming intrahepatic cholangiocarcinoma: A case series of 68 patients

Table 4 Univariate and multivariate analyses of clinical and pathological factors for overall survival of patients in the surgery group

Variable	Patients (n)	1 yr (%)	3 yr (%)	5 yr (%)	P value	HR	95%CI	P value
Age (yr)					0.633
≤ 54	27	92.3	48.6	21.2
> 54	22	95.0	50.7	9.5
Gender					0.441
Male	34	90.9	48.2	18.1
Female	15	100.0	54.0	13.5
HBV infection					0.063
Yes	13	92.3	30.8	0
No	36	94.0	57.1	22.5
Ascites					0.836
Present	1	0	0	0
Absent	48	93.4	49.6	14.4
Tumor size (cm)					0.044	1.273	0.485-3.339	0.624
≤ 7	28	92.9	69.6	16.9
> 7	21	94.1	33.6	8.4
CA 19-9 (IU/mL)					0.571
≤ 27	26	96.0	53.9	12.9
> 27	23	90.6	43.7	19.4
Differentiation					0.061
Poor	20	89.7	34.5	0
Poor-moderate	19	94.7	73.9	23.9
Moderate	10	100.0	35.7	35.7
Nodal metastasis					0.001	3.221	1.364-7.610	0.008
Yes	35	97.0	64.0	21.7
No	14	85.7	11.9	0
Tumor location					0.545
Left lobe	11	100.0	66.7	33.3
Right lobe	38	91.4	46.3	13.0
Vascular invasion					< 0.001	3.148	1.160-8.544	0.024
Yes	12	83.3	16.7	0
No	37	97.1	66.3	22.2
Pattern of liver resection					0.773
AR resection	23	96.0	50.6	11.4
NAR resection	25	95.5	51.7	9.7
Resection margin(cm)					0.361
≤ 1	21	95.2	40.3	16.1
> 1	27	96.0	57.3	14.6

CA19-9: Carbohydrate antigen 19-9.