Para-aortic lymph node involvement should not be a contraindication to resection of pancreatic ductal adenocarcinoma

Table 2 Risk analysis for overall survival

	Univariable		Multivariable
	P value	HR (CI)	P value	HR (CI)
Age	0.668	0.994 (0.966-1.022)
Sex	0.359	0.756 (0.416-1.374)
Preoperative CA19-9	0.626	1.000 (1.000-1.000)
Pre-operative stage	0.949	0.986 (0.641-1.517)
Resection type	0.517	1.141 (0.765-1.702)
Venous resection	0.659	1.146 (0.625-2.104)
Arterial resection	0.327	2.045 (0.489-8.559)
pT	0.001	2.148 (1.368-3.371)	0.008
pT1			0.842	1.114 (0.385-3.226)
pT2			0.115	2.459 (0.803-7.536)
pT3			0.008	31.275 (2.491-392.605)
pN	0.002	2.195 (1.337-3.604)	0.004
pN1			0.329	2.332 (0.427-12.740)
pN2			0.016	7.564 (1.459-39.224)
PALN positivity	0.041	1.970 (1.028-3.776)
Margin status	0.007	2.331 (1.261-4.308)	0.049	1.986 (1.003-3.932)
Perineural invasion	0.212	1.691 (0.741-3.861)
Perivascular invasion	0.464	1.278 (0.663-2.461)
Chemotherapy	0.033	0.487 (0.251-0.944)	0.002	0.283 (0.129-0.622)

All parameters with P < 0.200 on univariable entered into multivariable model. HR: Hazard ratios; CI: Confidence intervals; PALN: Para-aortic lymph nodes.