Development of a warning score for early detection of colorectal anastomotic leakage: Hype or hope?

Table 4 Sensitivity, specificity, positive predictive value, and negative predictive value for the Early ColoRectAL Leakage score according to the postoperative day

E-CRALL score	POD3	POD4	POD5
Threshold	5.51	2.56	8.29
Sensitivity, %	85.7	100	100
Specificity, %	66.1	69.6	86.6
PPV	13.8	17.2	32.1
NPV	98.7	100	100
CAL diagnosis, %	67.2	71.4	87.4
AUROC (95%CI)	0.82 (0.67-0.96)	0.84 (0.74-0.94)	0.95 (0.90-0.99)

AUROC: Area under the receiver operating characteristic curve; CAL: Colorectal anastomotic leakage; CI: Confidence interval; E-CRALL: Early ColoRectAL Leakage score; NPV: Negative predictive value; POD: Postoperative day; PPV: Positive predictive value.