Development of a warning score for early detection of colorectal anastomotic leakage: Hype or hope?

Table 3 Items weighted for the early ColoRectAL leakage score from postoperative day 3 to 5

E-CRALL score	POD3	POD4	POD5
Body mass index	-0.05142	-0.02927	Not included
Charlson Comorbidity Index score	0.1403	Not included	Not included
Open surgery	Not included	-0.0196	Not included
ASA score III or IV	0.0764	Not included	Not included
Blood loss (in mL)	0.2418	0.2044	0.1426
Operative time (in min)	0.0070	0.0074	0.0041
Anastomosis colocolic	-0.1065	-0.0297	Not included
Intraoperative complications	1.1731	1.378	0.7685
Plasma level of CRP (in mg/L)	0.0099	0.0089	0.0066
Plasma level of CLP (in μg/mL)	0.1333	0.1809	0.4548
Plasma level of ECC (in cell/μL)	Not included	-0.0007	-0.0038
Clinical condition: improved	Not included	-0.6075	-2.199
Abdominal pain (absent/low)	Not included	-1.1150	-0.2843
Abdominal pain (at wound)	-1.19011	-1.845	-1.5299
Abdominal pain (localized)	Not included	Not included	1.2566

ASA: American Society of Anesthesiologists; CLP: Calprotectin; CRP: C-reactive protein; ECC: Eosinophil cell count; E-CRALL: Early ColoRectAL Leakage score; POD: Postoperative day.